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008			200827s2020 si a s |||| 0|eng d
020			_a9789811561290
024	7		_a10.1007/978-981-15-6129-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRA1226 _b2020 EB
100	1		_aWang, Dayong _eautor _4http://id.loc.gov/vocabulary/relators/aut _9669903
245	1	0	_aExposure Toxicology in Caenorhabditis elegans _cby Dayong Wang
250			_aFirst edition 2020
264		1	_aSingapore _bSpringer Singapore _c2020
300			_a1 recurso en línea (XIX, 682 páginas) _b447 ilustraciones, 303 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (SpringerNature-43708)
505	0		_a1. Exposure Durations of Environmental Stresses or Toxicants -- 2. Exposure Stages of Environmental Stresses or Toxicants -- 3. Complex Exposures to Environmental Toxicants or Stresses -- 4. Transgenerational Toxicity of Environmental Toxicants or Stresses -- 5. Exposure Routes of Environmental Toxicants -- 6. Basic Endpoints for Toxicity Assessment of Environmental Toxicants or Stresses -- 7. Endpoints for Assessing the Toxicity on Primary Targeted Organs -- 8. Endpoints for Assessing the Toxicity on Secondary Targeted Organs -- 9. Endpoints for Assessing the Toxicity on Biochemical Processes -- 10. Endpoints for Assessing the Genotoxicity and the Genetic Toxicity -- 11. Role of Exposure Dose in Toxicity Induction of Environmental Toxicants or Stresses -- 12. Role of Environmental Factors in Toxicity Induction of Environmental Toxicants or Stresses -- 13. Effects of Environmental Sample Forms on Toxicity Induction -- 14. Roles of Physicochemical Properties of Toxicants in Toxicity Induction -- 15. Roles of Environmental Media and Chemical Transformations of Environmental Toxicants in Toxicity Induction -- 16. Bioavailability, Enrichment, and Translocation of Environmental Toxicants -- 17. Susceptibility to Toxicants or Stresses Induced by Genetic Mutations -- 18. Contributors to Amplify the Toxicity of Toxicants or Stresses -- 19. Exposure to Certain Environmental Stresses -- 20. High-Throughput Toxicity Assessment -- 21. Toxicity Assessment under the Pathological Conditions.
520	3		_aThis book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans
988			_aSpringer_BiomedLife_13102020
650		7	_2embne _aToxicología ambiental _9159275
650		7	_2embne _aFarmacología _9137893
710	2		_aSpringerLink
776	0	8	_iPrinted edition: _z9789811561283
776	0	8	_iPrinted edition: _z9789811561306
776	0	8	_iPrinted edition: _z9789811561313
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-6129-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2021 _dz _ek _zSI