| 000 | 03287nam a22004335i 4500 | ||
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| 999 |
_c127417 _d127417 |
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| 001 | 127417 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230102114245.0 | ||
| 006 | a||||fo|||| 00| 0 | ||
| 007 | cr nn nnnaamaa | ||
| 008 | 200810s2020 gw a s |||| 0|eng d | ||
| 020 | _a9783030396848 | ||
| 024 | 7 |
_a10.1007/978-3-030-39684-8 _2doi |
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| 040 |
_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC |
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| 050 | 4 |
_aQP752.S75 _b2020 EB |
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| 245 | 0 | 0 |
_aMammalian Sterols : _bNovel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids _cedited by Damjana Rozman, Rolf Gebhardt. |
| 250 | _aFirst edition 2020 | ||
| 264 | 1 |
_aCham _bSpringer International Publishing _c2020 |
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| 300 |
_a1 recurso en línea (V, 171 páginas) _b57 ilustraciones, 14 ilustraciones a color |
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| 336 |
_2rdacontent _aTexto _btxt |
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| 337 |
_2rdamedia _aelectrónico _bc |
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| 338 |
_2rdacarrier _arecurso electrónico _bcr |
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| 347 |
_aArchivo de texto _bPDF |
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| 490 | 0 | _aBiomedical and Life Sciences (SpringerNature-11642) | |
| 490 | 0 | _aBiomedical and Life Sciences (SpringerNature-43708) | |
| 505 | 0 | _aSterols from the post-lanosterol part of cholesterol synthesis - novel signaling players -- Genetic variability in cholesterol metabolism -- Side-chain oxidized oxysterols in health and disease -- Bile acids and TGR5 (Gpbar1) signaling -- Bile acids as regulatory signalling molecules -- Oxysterols and bile acid act as signaling molecules that regulate cholesterol homeostasis: nuclear receptors LXR, FXR, and fibroblast growth factor 15/19 -- Cytochrome P450 Metabolism Leads to Novel Biological Sterols and Other Steroids. | |
| 520 | 3 | _aThis book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease. It offers insight into new research findings, focusing specifically on novel discoveries in bile acid and oxysterol signaling, including the lanosterol-to-cholesterol intermediates. Special attention is paid on the sex distribution of these sterols (male or female) and their sexually dimorphic roles in mammalian species, such as human, rat and mouse. Since sterols and drugs (xenobiotics) use many identical receptor-mediated signaling pathways, the book will be interesting for researchers working on the cross-road of endogenous and xenobiotic metabolism, it is intended for advanced students and scientists in molecular biology and biochemistry as well as medical doctors in hepatology. | |
| 988 | _aSpringer_BiomedLife_13102020 | ||
| 650 | 7 |
_2embne _aLípidos _9142933 |
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| 700 | 1 |
_aRozman, Damjana _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aGebhardt, Rolf _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 710 | 2 | _aSpringerLink | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030396831 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030396855 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030396862 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-39684-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 942 |
_2lcc _cLE |
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| 998 |
_b11/2020 _dz _ek _zSI |
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