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020 _a9783030580049
024 7 _a10.1007/978-3-030-58004-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQR189
_b2020 EB
245 0 0 _aVaccination Strategies Against Highly Variable Pathogens
_cedited by Lars Hangartner, Dennis R. Burton
250 _aFirst edition 2020
264 1 _aCham
_bSpringer International Publishing
_c2020
300 _a1 recurso en línea (VII, 180 páginas)
_b16 ilustraciones, 15 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aCurrent Topics in Microbiology and Immunology
_x0070-217X
_v428
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (SpringerNature-43708)
505 0 _aSuccessful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
520 3 _aVaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine
988 _aSpringer_BiomedLife_13102020
650 7 _2embne
_aVacunas
_9140409
700 1 _aHangartner, Lars
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBurton, Dennis R
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink
776 0 8 _iPrinted edition:
_z9783030580032
776 0 8 _iPrinted edition:
_z9783030580056
776 0 8 _iPrinted edition:
_z9783030580063
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-58004-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b11/2020
_dz
_ek
_zSI