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020 _a9789813290051
024 7 _a10.1007/978-981-32-9005-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP86
_b2020 EB
245 0 0 _aModels, Molecules and Mechanisms in Biogerontology :
_bCellular Processes, Metabolism and Diseases
_cedited by Pramod C. Rath
250 _aFirst edition
264 1 _aSingapore
_bSpringer
_c2020
300 _a1 recurso en línea (XIII, 497 páginas)
_b77 ilustraciones, 70 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aPART I ~ ALTERATIONS IN CELLULAR MECHANISMS DURING AGING -- Chapter 1 Protein Structure and Function in Aging and Age-related Diseases -- Chapter 2 DNA, DNA Replication and Aging -- Chapter 3 Transcription and Aging -- Chapter 4 Ribosomes, Translation and Aging -- Chapter 5 p53 and Aging -- Chapter 6 Paired Box (Pax) Transcription Factors and Aging -- Chapter 7 Telomeres, Telomerase and Aging -- Chapter 8 The Epigenome of Ageing -- Chapter 9 Attaining Epigenetic Rejuvenation: Challenges Ahead -- Chapter 10 Mitochondria as a Key Player in Aging -- Chapter 11 Aging, Free Radicals and Reactive Oxygen Species: An Evolving Concept -- Chapter 12 Stem Cells and Aging -- Chapter 13 Can Autophagy Stop the Clock: Unravelling the Mystery in Dictyostelium discoideum -- Chapter 14 Aging: Reading, Reasoning and Resolving Using Drosophila as a Model System -- Chapter 15 Nothobranchius furzeri as a New Model System for Aging Studies -- PART II ALTERATIONS IN METABOLISM DURING AGING AND DISEASES -- Chapter 16 Aging in Muscle -- Chapter 17 Metabolic Diseases and Aging -- Chapter 18 Interplay Between Nutrient Sensing Molecules During Aging and Longevity -- Chapter 19 Protein Aggregation, Related Pathologies and Aging -- Chapter 20 Biological Rhythms and Aging -- Chapter 21 The Biology of Ageing and Cancer - A Complex Association.
520 _aThe book deals with basic cellular and molecular mechanisms associated with aging. It comprehensively describes the important genetic, epigenetic, biochemical and metabolic regulations during aging, as well as some important age-related diseases.The book is divided into four major sections for easy understanding. It takes the readers through the various aspects of aging in a story-like manner. Certain interventions for healthy aging such as dietary restriction, regular exercise and maintaining a balanced and peaceful life-style are also suggested by the experts. The book would be a companion for both beginners, as well as established researchers in the field. It would be useful for science education, research, clinical approach and policy making.
988 _aSpringer_Biomedlife_03082020
650 7 _2embne
_9141231
_aEnvejecimiento
650 7 _2embne
_9162368
_aBiología del desarrollo
700 1 _aRath, Pramod C.
_eeditor literario
_4http://id.loc.gov/vocabulary/relators/edt
_1http://viaf.org/viaf/4021149235096976690002
_9675450
776 0 8 _iPrinted edition:
_z9789813290044
776 0 8 _iPrinted edition:
_z9789813290068
776 0 8 _iPrinted edition:
_z9789813290075
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-32-9005-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b08/2020
_dz
_ek
_zSI