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008			200529s2020 gw | s |||| 0|eng d
020			_a9783030431570
024	7		_a10.1007/978-3-030-43157-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRG628.3.P74 _b2020 EB
100	1		_aKuliev, Anver _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n89143498 _1http://viaf.org/viaf/22212524 _9675964
245	1	0	_aPractical Preimplantation Genetic Testing _cby Anver Kuliev, Svetlana Rechitsky, Joe Leigh Simpson.
250			_a3rd ed. 2020.
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2020
300			_a1 recurso en línea (XII, 291 páginas) _b118 ilustraciones, 62 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aMedicine (Springer-11650)
505	0		_aPlace of Preimplantation Genetic Testing (PGT) in the Options for Primary Prevention of Genetic Disorders -- Major Components of Preimplantation Genetic Testing: Obtaining Biopsy Material -- Major Components of Preimplantation Genetic Testing: Adjustment of Available Genetic Technologies to PGT Practice -- Strategies and Indications for Preimplantation Genetic Testing of Monogenic Disorders (PGT-M) -- Preimplantation Genetic Testing for Human Leucocyte Antigens (HLA) (PGT-HLA) -- Preimplantation Genetic Testing for Chromosomal Disorders -- Clinical Outcomes of Preimplantation Genetic Testing -- Ethical, Social and Legal Issues with Preimplantation Genetic Testing.
520	3		_aFully revised and updated with the most current information, the third edition of this practical clinical text covers all aspects of the rapidly advancing field of preimplantation genetic testing (PGT). Although PGT has become an established procedure for genetics and assisted reproduction practices over the last decade, its wider application has occurred after the introduction of next generation technologies in the last few years, necessitating this much-needed new edition. This will include, first of all, an update on PGT accuracy, reliability and safety, to ensure improved access to PGT for those who may benefit greatly from this technology. New content will also present progress in the primary prevention of genetic disorders, which now discusses approaches for prospective identification of at-risk PGT couples through the application of the extended gene testing panels. In fact, because of dramatic technological improvements in all aspects of PGT, most of the sections have been updated, with the addition of new sections on next generation technologies and universal PGT with combined testing for single gene and chromosomal disorders, which has previously presented a challenge. The guiding PGT strategies for different genetic disorders are presented, with emphasis on the most complicated cases that might be of special utility in the wider application PGT technologies worldwide. Additionally, a new section will be devoted to borderline indications, which will include common adult-onset conditions with genetic predisposition and non-genetic indications, expanding PGT applications to heart disease and cancer and the use of PGT for stem cell transplantation treatment of genetic and acquired disorders, where unique outcome data has become available. Combining the latest research and the most cutting-edge practice, Practical Preimplantation Genetic Testing, 3e is an excellent resource for clinical reproductive medicine specialists, genetic counselors, researchers and analysts.
988			_aSpringer_Medicine_2020
650		7	_2embne _9510497 _aDiagnóstico genético preimplantatorio
650		7	_2embne _aObstetricia _9137907
650		7	_2embne _aSalud reproductiva _9162207
700	1		_aRechitsky, Svetlana. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2014180435 _1http://viaf.org/viaf/307434270
700	1		_aSimpson, Joe Leigh. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _1http://viaf.org/viaf/1327575
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9783030431563
776	0	8	_iPrinted edition: _z9783030431587
776	0	8	_iPrinted edition: _z9783030431594
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-43157-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2020 _dz _eIG _zSI