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005			20230102114102.0
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007			cr nn nnnaamaa
008			200527s2020 gw | s |||| 0|eng d
020			_a9783030430597
024	7		_a10.1007/978-3-030-43059-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC376.5 _b2020 EB
100	1		_aTermsarasab, Pichet _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9675955
245	1	0	_aStiff-Person Syndrome and Related Disorders : _bA Comprehensive, Practical Guide _cby Pichet Termsarasab, Thananan Thammongkolchai, Bashar Katirji
250			_a1st ed. 2020.
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2020
300			_a1 recurso en línea (XV, 183 páginas) _b46 ilustraciones, 20 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aMedicine (Springer-11650)
505	0		_aHistorical background of stiff-person syndromes -- Clinical phenomenology and diagnostic criteria of stiff-person syndrome and stiff-person syndrome variants -- Differential diagnosis of stiff-person syndromes -- Electrophysiology of stiff-person syndromes -- Neurochemistry of inhibitory synapses and clinical applications in stiff-person syndromes -- Immunopathogenesis of stiff-person syndromes -- Antibodies in stiff-person syndrome and their correlations with clinical phenotypes -- Anti-glutamic acid decarboxylase 65 (GAD65)-associated syndromes -- Progressive encephalomyelitis with rigidity and myoclonus (PERM) syndrome -- Emergencies in stiff-person syndrome -- Diagnostic approach in stiff-person syndrome and its variants -- Treatment of stiff-person syndromes -- Pediatric stiff-person syndromes -- Peripheral hyperexcitability syndromes -- Hyperekplexia.
520	3		_aThis comprehensive title covers all of the broad aspects of stiff-person spectrum disorders (SPSD), ranging from clinical features and laboratory investigations to the basic scientific roles of neuroimmunology and genetics that aid clinicians in understanding the pathogenesis of this disorder. Organized across 15 chapters, this highly practical book begins with a thorough account of the history and clinical phenomenology of SPSD. Subsequent chapters then delve into the differential diagnoses of the disorder, as well as its electrophysiology, immunopathogenesis, and neurochemistry. Following this is an analysis of each subtype of SPSD including classic stiff-person syndrome and its variants, correlations between clinical phenotypes and antibodies, as well as SPSD in the pediatric population. Finally, the book concludes with an examination of the various SPSD diagnostic approaches, treatments, and potential emergencies seen in clinical practice. Developed by a renowned multidisciplinary authorship, Stiff-Person Syndrome and Related Disorders is an indispensable contribution to the clinical literature and will be of great interest to both clinicians and basic science researchers.
988			_aSpringer_Medicine_2020
650		7	_2embne _aSistema nervioso central _xEnfermedades _9188115
700	1		_aThammongkolchai, Thananan _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9675956
700			_aKatirji, Bashar _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n98800735 _1http://viaf.org/viaf/19005151 _988067
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9783030430580
776	0	8	_iPrinted edition: _z9783030430603
776	0	8	_iPrinted edition: _z9783030430610
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-43059-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2020 _dz _eIG _zSI