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008			200530s2020 xxua o |||| 0|eng d
020			_a9781071607411
024	7		_a10.1007/978-1-0716-0741-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC268.4 _b2020 EB
100	1		_aDas, Undurti N. _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _1http://viaf.org/viaf/53505236 _955596
245	1	0	_aMolecular Biochemical Aspects of Cancer _cUndurti N. Das
250			_aFirst edition
264		1	_aNew York _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XIII, 254 páginas) _b58 ilustraciones, 42 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aIntroduction to genes, oncogenes, and anti-oncogenes -- Introduction to free radicals (including nitric oxide), antioxidants, lipid peroxidation and their effects on cell proliferation -- Immune system, inflammation and essential fatty acids and their metabolites in cancer -- PUFAs and their metabolites in carcinogenesis -- Molecular mechanism of anti-cancer action of PUFAs with particular reference to GLA in glioma -- Bioactive lipids (BAL)-based therapeutic approach to cancer that enhances anti-tumor action and ameliorates cytokine release syndrome of immune check point inhibitors -- A new therapeutic strategy to treat cancer based on bioactive lipids (BAL) -- Index.
520	3		_aThis book discusses the role of genes, oncogenes, anti-oncogenes, free radicals, PUFAs, anti-oxidants, lipid peroxidation process, telomere, and angiogenesis on the origin of cancer, cell proliferation, and cancer in general. It includes a broad introduction to cancer cells; genes, oncogenes, and anti-oncogenes; and free radicals. In later chapters, it discusses in depth the relationship among free radicals, lipid peroxidation and anti-oxidants in cell proliferation. It also discusses aerobic and anaerobic metabolism and their relationship to cancer, as well as the Warburg effect and its potential in the development of new targets for cancer management. Based on these and other evidences, Molecular Biochemical Aspects of Cancer introduces a novel concept that suggests that selective enhancement of free radical generation in tumor cells could form a strategy to induce apoptosis of cancer cells employing bioactive lipids. It presents a new method of treatment of cancer using in vitro, in vivo and clinical data. This book will interest oncologists, scientists, molecular biologists, life scientists.
988			_aSpringer_Biomedlife_23062020
650		7	_aCáncer _xAspectos moleculares _2embne _9309464
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9781071607398
776	0	8	_iPrinted edition: _z9781071607404
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0741-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2020 _dz _eo _zSI