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008			200529s2020 gw a o |||| 0|eng d
020			_a9783030444365
024	7		_a10.1007/978-3-030-44436-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP517.C45 _b2020 EB
245	0	0	_aTissue-Specific Cell Signaling _cedited by Joana Vieira Silva, Maria João Freitas, Margarida Fardilha
250			_aFirst edition
264		1	_aCham, Switzerland _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XVIII, 436 páginas) _b51 ilustraciones, 50 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPreface -- Tissue-specific cell signaling: introduction -- Beyond the brain signaling -- Cell signaling within pituitary, the master gland of the endocrine system -- Cell signaling within endocrine glands: thyroid, parathyroids and adrenal glands -- Signaling pathways governing activation of innate immune cells -- Cell activation and signaling in lymphocytes -- Signaling pathways involved in kidney and urinary tract physiology and pathology -- More than androgens: hormonal and paracrine signaling in prostate development and homeostasis -- Testicular signaling: team work in sperm production -- Sperm signaling specificity: from sperm maturation until oocyte recognition -- Hormone signaling pathways in the postnatal mammary gland -- Oogenesis signaling: from development to environmental plasticity and aging -- Key signaling pathways in the cardiovascular system -- Growth factor signaling in the maintenance of adult lung homeostasis -- The signaling pathways involved in the regulation of skeletal muscle plasticity -- Adipocyte-specific signaling.
520	3		_aSignal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
988			_aSpringer_Biomedlife_23062020
650		7	_aTransducción de la señal celular _2embne _9689361
700	1		_aSilva, Joana Vieira _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/361144782738903907217
700	1		_aFreitas, Maria João _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n94093618 _1http://viaf.org/viaf/4167486
700	1		_aFardilha, Margarida _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9783030444358
776	0	8	_iPrinted edition: _z9783030444372
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-44436-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2020 _dz _eo _zSI