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008			200422s2020 si a o |||| 0|eng d
020			_a9789811535321
024	7		_a10.1007/978-981-15-3532-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR185.8.B15 _b2020 EB
245	0	0	_aB Cells in Immunity and Tolerance _cedited by Ji-Yang Wang
250			_aFirst edition
264		1	_aSingapore _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XII, 181 páginas) _b35 ilustraciones, 30 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1254
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aB cell development and maturation -- B cell receptor signalling -- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger -- Germinal center reaction -- Memory B cells in local and systemic sites -- Regulation of plasma cell differentiation -- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor -- Regulatory B cells -- Diversified IgA-bacteria interaction in gut homeostasis -- Primary antibody deficiencies -- B cell-mediated autoimmune diseases -- B cell lymphomas.
520	3		_aThis book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
988			_aSpringer_Biomedlife_23062020
650		7	_aLinfocitos B _2embne _9675040
650		7	_aMedicina experimental _2embne _9146841
650		7	_aBiología _2embne _9138150
700	1		_aWang, Ji-Yang _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9789811535314
776	0	8	_iPrinted edition: _z9789811535338
776	0	8	_iPrinted edition: _z9789811535345
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1254
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-3532-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2020 _dz _eo _zSI