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008			200417s2020 si a o |||| 0|eng d
020			_a9789811523892
024	7		_a10.1007/978-981-15-2389-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQM691 _b2020 EB
245	0	0	_aAnimal Models of Human Birth Defects _cedited by Aimin Liu
250			_aFirst edition
264		1	_aSingapore _bSpringer International Publishing _c2020
300			_a1 recurso en línea (VII, 244 páginas) _b54 ilustraciones, 43 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1236
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aChapter 1: Using forward and reverse genetics in mouse to study birth defects -- Chapter 2: Using animals to study neural tube defects -- Chapter 3: Using animals to study ciliopathies -- Chapter 4: Using animals to model human skeletal defects -- Chapter 5: Understanding eye defects using animal models -- Chapter 6: Modelling kidney and urinary tract defects in animals -- Chapter 7: Pancreas development and type I diabetes -- Chapter 8: Using animals to study human birth defects affecting the functions of the digestive system -- Chapter 9: Modelling human birth defects with zebrafish -- Chapter 10: Modelling diseases with C. elegans -- Chapter 11: Infectious disease and birth defects.
520	3		_aThis book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
988			_aSpringer_Biomedlife_23062020
650		7	_aMalformaciones congénitas _xInvestigación _2embne _9138039
650		7	_aMalformaciones congénitas _2embne _9138039
700	1		_aLiu, Aimin _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nr99030718 _1http://viaf.org/viaf/193482574
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9789811523885
776	0	8	_iPrinted edition: _z9789811523908
776	0	8	_iPrinted edition: _z9789811523915
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1236
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-2389-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2020 _dz _eo _zSI