000			04074nam a22004335i 4500
999			_c120571 _d120571 _x1
001			120571
003			ES-MaUEC
005			20230102114049.0
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
008			200518s2020 gw a o |||| 0|eng d
020			_a9783030422462
024	7		_a10.1007/978-3-030-42246-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQL537.D76 _b2020 EB
245	0	0	_aMolecular Genetics of Axial Patterning, Growth and Disease in Drosophila Eye _cedited by Amit Singh, Madhuri Kango-Singh
250			_aSecond edition
264		1	_aCham, Switzerland _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XIV, 368 páginas) _b81 ilustraciones, 73 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aEarly eye development: Specification and Determination -- Generation of third dimension: Axial patterning in the developing Drosophila eye -- Catching the Next Wave: Patterning of the Drosophila eye by the Morphogenetic Furrow -- Ghost in the Machine- the Peripodail Epithelium -- Cell Polarity in Drosophila Retina -- Negative regulation for neural patterning in the Drosophila eye -- Adhesion and the cytoskeleton in the Drosophila pupaleye -- Drosophila eye as a model to study regulation of growth control: The discovery of size control pathways -- Drosophila cancer modeling using the eye imaginal discs -- Recent contributions of the Drosophila eye to unraveling the basis of neurodegeneration -- Genetic regulation of early eye development in non-dipteran insects -- Eyes for an eye: A comparative account on compound eye of Drosophila melanogaster with vertebrate eye -- Index.
520	3		_aDrosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology is how a multi-cellular organism develops from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question and has led to other questions, such as the role of various genetic and cell biological pathways in regulating the process of pattern formation and growth during organogenesis. The Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This updated second edition covers current progress in the study of molecular genetic mechanisms of pattern formation, mutations in axial patterning, genetic regulation of growth, and more using the Drosophila eye as a model.
988			_aSpringer_Biomedlife_23062020
650		7	_aDrosofílidos _2embne _9145447
650		7	_aGenética humana _2embne _9140562
700	1		_aSingh, Amit _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n2006035053 _1http://viaf.org/viaf/70814991
700	1		_aKango-Singh, Madhuri _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n2018181827 _1http://viaf.org/viaf/315256019
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729
776	0	8	_iPrinted edition: _z9783030422455
776	0	8	_iPrinted edition: _z9783030422479
776	0	8	_iPrinted edition: _z9783030422486
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-42246-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2020 _dz _eo _zSI