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008			200214s2020 gw | o |||| 0|eng d
020			_a9783030344368
024	7		_a10.1007/978-3-030-34436-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP517.C45 _b2020 EB
245	0	0	_aNotch Signaling in Embryology and Cancer _bNotch Signaling in Embryology _cedited by Jörg Reichrath, Sandra Reichrath.
250			_aFirst edition 2020
264		1	_aCham, Switzerland _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XIII, 195 páginas) _b16 ilustraciones, 5 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1218
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aNotch signalling and embryology: an introduction -- Notch signaling and embryonic development: an ancient friend, revisited -- The Five Faces of Notch Signalling During Drosophila melanogaster Embryonic CNS Development -- Epigenetic regulation of Notch signaling during Drosophila development -- Regulation of proneural wave propagation through a combination of Notch-mediated lateral inhibition and EGF-mediated reaction diffusion -- A nucleolar protein, Nepro, is essential for the maintenance of early neural stem cells and preimplantation embryos -- The role of Notch signaling in leg development in Drosophila melanogaster -- Notch pathway and inherited diseases: challenge and promise -- Index.
520	3		_aThis thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books - Molecular Biology of Notch Signaling and Notch Signaling in Cancer - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students. .
988			_aSpringer_BiomedLife_31032020
650		7	_2embne _aTransducción de la señal celular _9689361
700	1		_aReichrath, Jörg. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aReichrath, Sandra. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service)
776	0	8	_iPrinted edition: _z9783030344351
776	0	8	_iPrinted edition: _z9783030344375
776	0	8	_iPrinted edition: _z9783030344382
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://dx.doi.org/10.1007/978-3-030-34436-8
942			_2lcc _cLE _n0
998			_b04/2020 _dz _eb _zSI