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020 _a9783030404130
024 7 _a10.1007/978-3-030-40413-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRF290
_b2020 EB
245 0 0 _aNew Therapies to Prevent or Cure Auditory Disorders
_cedited by Sylvie Pucheu, Kelly E. Radziwon, Richard Salvi
250 _aFirst edition 2020
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2020
300 _a1 recurso en línea (VII, 186 páginas)
_b29 ilustraciones, 25 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
520 3 _aThis volume focuses on new molecular therapies that aim to prevent specific pathologies of the ear, like age-related hearing loss, noise-induced hearing loss and ototoxicity. The book discusses the regenerative capacity of hair cells in the inner ear, exploring the idea that hair cells' capacity to regenerate appears "repressed" in adult mammals, but that it will be possible to re-activate regeneration with an appropriate therapeutic approach. The book provides an overview of inflammatory and immune cells in the cochlear lateral wall, the pathways involved in cochlear damage, and their potential as therapeutic targets. It also describes the significant advances in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis. Finally, the book describes two new automatic and robust measures to evaluate hearing loss and tinnitus in preclinical models.
988 _aSpringer_BiomedLife_31032020
650 7 _2embne
_aAudición
_xTrastornos
_9168808
650 7 _2embne
_aOtorrinolaringología
_9138570
700 1 _aPucheu, Sylvie.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRadziwon, Kelly E.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSalvi, Richard.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
776 0 8 _iPrinted edition:
_z9783030404123
776 0 8 _iPrinted edition:
_z9783030404147
776 0 8 _iPrinted edition:
_z9783030404154
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://dx.doi.org/10.1007/978-3-030-40413-0
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998 _b04/2020
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