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020 _a9783030169961
024 7 _a10.1007/978-3-030-16996-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC1135
_b2020 EB
245 0 0 _aStress Challenges and Immunity in Space :
_bFrom Mechanisms to Monitoring and Preventive Strategies
_cedited by Alexander Choukèr.
250 _a2nd ed. 2020.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2020.
300 _a1 recurso en línea (XVI, 771 páginas)
_b137 ilustraciones, 112 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _aPart I Prelude -- 1 Space Travel: A Personal View from Above -- 2 Prelude: An integrative and up-dated view from the Scientists of the Topical Team "Stress and Immunity" -- Part II "Stress and Immunity" - Research: A Link Between Space and Earth -- 3 What Is Stress? -- 4 The special relation of mitochondria, metabolism and stress -- 5 The Impact of Everyday Stressors on the Immune- System and Health -- Part III Stress and Immune Allostasis in Space, from Brain to Immune Responses -- 6 Neurobiological and Molecular Mechanisms of Stress and Glucocorticoid Effects on Learning and Memory: Implications for Stress Disorders on Earth and in Space -- 7 The Autonomic Nervous System -- 8 Circadian Rhythm and Stress -- 9 Endocannabinoids, "New-Old" Mediators of Stress Homeostasis -- 10 Immune System in Space: General Introduction and Observations on Stress-Sensitive Regulations -- 11 Innate Immunity Under Conditions of Space Flight -- 12 NK Cells Assessments: A Fourty-Year-Old History of Immune Stress Interaction in Space -- 13 Adaptive Immunity and Spaceflight -- 14 B-cell Immunology in Space -- 15 Stress, Hypoxia, and Immune Response -- 16 Gravitational Force: Triggered Stress in Cells of the Immune System -- 17 Microbial Stress: Spaceflight-induced Alterations in Microbial Virulence and Infectious Disease Risks for the Crew -- 18 Stress, Spaceflight, and Latent Herpes Virus Reactivation -- 19 Stress and Radiation-Immune-Responsiveness -- Part IV Preventive and Diagnostic Tool and Strategies -- 20 Considerations for Development and Application of Health Monitoring Tools in Space -- 21 Psychological Monitoring -- 22 Technology up-date for monitoring Autonomic Activity -- 23 Breath Gas Analysis -- 24 Monitoring the Microbial Burden in Manned Space Stations and Analogue environments -- 25 Monitoring of Body Core Temperature in Space -- 26 Flow Cytometry and cryopreservation Methods to Monitor Immune Dysregulation Associated with Spaceflight -- 27 Assessment of Radiosensitivity and Monitoringof Radiation-Induced Cellular Damage -- 28 Hair analyses - growing evidence -- Part V Therapeutic Strategies -- 29 Considerations for Preventive and Therapeutic Strategies -- 30 Psychological Countermeasures -- 31 Physical Countermeasures to Stress -- 32 Nutritional Countermeasures for Spaceflight-Related Stress -- 33 The Microbiome perspective: Immune - gut- axis modulation -- 34 Pharmacological Countermeasures to Spaceflight-Induced Alterations of the Immune System -- Part VI Perspectives for Manned Space Exploration - from Visions to Realities -- 35 Platforms for Stress and Immune Research in Preparation of Long-Duration Space Exploration Missions -- 36 MARS500 the first preparation of Long-Duration Space Exploration Missions - lessons learned for space exploration and health on Earth -- 37 On the ICE: Isolated, Confined and Extreme Environment -- 39 Moon, Mars and Beyond- the exploration roadmap and further visions. .
520 3 _aThis book explains how stress - either psychological or physical - can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors - the space exposome - on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters "The Impact of Everyday Stressors on the Immune System and Health", "Stress and Radiation Responsiveness" and "Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
988 _aSpringer_Medicine_2020
650 7 _2embne
_9145917
_aMedicina aeroespacial
700 1 _aChoukèr, Alexander
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_999803
776 0 8 _iPrinted edition:
_z9783030169954
776 0 8 _iPrinted edition:
_z9783030169978
776 0 8 _iPrinted edition:
_z9783030169985
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-16996-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
_n0
998 _b04/2020
_dz
_ea
_zSI