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020 _a9783319692876
024 7 _a10.1007/978-3-319-69287-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC931.O73
_b2020 EB
245 0 0 _aOsteoporosis.
_bPathophysiology and Clinical Management
_cedited by Benjamin Z. Leder, Marc N. Wein.
250 _a3rd ed. 2020.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Humana
_c2020.
300 _a1 recurso en línea (XV, 516 páginas)
_b82 ilustraciones, 46 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aContemporary Endocrinology
_x2523-3785
490 0 _aMedicine (Springer-11650)
505 0 _aBasic Aspects of Osteoblast Function -- Basic Aspects of Osteoclast Differentiation and Function -- Basic Aspects of Osteocyte Function -- Vitamin D and Bone Health: Basic and Clinical Aspects -- Basic Aspects of Bone Mineralization -- Determinants of Peak Bone Mass Acquisition -- Osteoporosis Screening and Diagnosis -- New Imaging Techniques for Bone -- Biochemical Markers of Bone Turnover -- Biomechanics of Bone -- Exercise in the Prevention of Osteoporosis-Related Fractures -- Effects of Estrogens and SERMs on Bone Metabolism: Clinical Aspects -- The Effects of Androgens on Bone Metabolism: Clinical Aspects -- Bisphosphonates: Mechanisms of Action and Role in Osteoporosis Therapy -- Denosumab: Mechanisms and Therapeutic Effects in the Treatment of Osteoporosis -- The Parathyroid Hormone Receptor Type 1 -- PTH and PTHrP Analogs: Treatment of Osteoporosis -- Combination and Sequential Osteoanabolic/Antiresorptive Therapy in Osteoporosis Treatment -- Sclerostin Inhibition in the treatment of Osteoporosis -- Osteoporosis in Men. Glucocorticoid-Induced Osteoporosis -- Transplantation Osteoporosis -- Osteoporosis in Premenopausal Women -- Safety Considerations for Osteoporosis Therapies -- Genetic Determinants and Pharmacogenetics of Osteoporosis and Osteoporotic Fracture.
520 3 _aCompletely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, including 300,000 hip fractures. Mortality rates after hip fracture approach 25%, with another 50% of patients experiencing a major decrease in their prior level of independence and quality of life. Despite the wide prevalence and severe consequences of osteoporosis, it remains a disorder that is severely under-diagnosed and treated. In this context, specialists and primary care physicians alike are having increasing difficulty keeping up with the rapid changes to the field and incorporating these advances to clinical care. In the years since the last edition of this book was published, the osteoporosis field has changed drastically. In addition to revising and updating existing chapters and removing a few that are no longer as relevant, new chapters discuss an advanced understanding of the cellular and molecular mechanisms underlying the disorder, the introduction of new diagnostic imaging techniques, a more nuanced appreciation of the risks and benefits of osteoporosis therapies, and the introduction of two new classes of osteoporosis medications. Following the format of the second edition, and including helpful key points at the opening of each chapter, this text will present a comprehensive overview of both the basic and clinical concepts relating to each topic, when appropriate. Chapter authors were chosen based on their high level of expertise and leadership in the field. Taken together, this text should thus be of great interest to physicians of multiple specialties, allied health professionals, as well as basic and clinical researchers.
988 _aSpringer_Medicine_2020
650 7 _2embne
_9141478
_aOsteoporosis
700 1 _aLeder, Benjamin Z.
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWein, Marc N.
_eeditor
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776 0 8 _iPrinted edition:
_z9783319692869
776 0 8 _iPrinted edition:
_z9783319692883
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-69287-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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998 _b03/2020
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