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020			_a9789811511691
024	7		_a10.1007/978-981-15-1169-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH603.P47 _b2019 EB
245	0	0	_aPeroxisomes: Biogenesis, Function, and Role in Human Disease _cedited by Tsuneo Imanaka, Nobuyuki Shimozawa.
250			_aFirst edition
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XII, 279 páginas) _b65 ilustraciones, 33 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPart 1 Biogenesis and Function of peroxisome -- 1 The history of peroxisomal research -- 2 Peroxisome Biogenesis -- 3 Peroxisome Degradation and Its Molecular Machinery -- 4 The function of the peroxisome -- Part 2 Dysfunction of Peroxisome and Human Disease -- 5 Peroxisomal disorders -- 6 Model organisms used to understand peroxisomal disorders -- 7 Diagnosis of peroxisomal disorders -- 8 Therapeutic strategies for X-linked adrenoleukodystrophy, a representative peroxisome disease -- Part 3 Topics in Peroxisome Research -- 9 The isolation of peroxisomes -- 10 Structure Biology of peroxisomal proteins, peroxins -- 11 Lipidomics of peroxisomal disorders -- 12 Neurophysiology and neuropsychology for X-ALD. .
520	3		_aThis book provides readers with a comprehensive overview of peroxisomes and their role in human diseases. It starts by describing the history of peroxisome research and then examines in detail the current understanding of the biogenesis and function of peroxisomes. It then focuses on peroxisomal disorders and the involvement of peroxisomes in cancer and age-related diseases, discussing in detail the use of model organisms to elucidate the pathogenesis of peroxisomal disorders and the physiological importance of peroxisomal proteins. Further, the book examines diagnostic and therapeutic strategies in peroxisomal disorders as well as significant recent advances. Lastly, it addresses various topics in peroxisome research, including the isolation of peroxisomes from mammalian tissues and cells, the structural biology of peroxisomal proteins, the lipidomics of peroxisomal disorders, the value of exome sequencing, and neuropsychological testing in X-linked adrenoleukodystrophy. Given its scope, the book is a valuable resource for postgraduate students and researchers in the life sciences and clinicians in the fields of internal medicine, pediatrics, and neurology.
988			_aPrimersemestre_2020_BiomedLife
650		7	_2embne _aCitología _9139477
700	1		_aImanaka, Tsuneo _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aShimozawa, Nobuyuki _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789811511684
776	0	8	_iPrinted edition: _z9789811511707
776	0	8	_iPrinted edition: _z9789811511714
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-1169-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b02/2020 _dz _ek _zSI