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020 _a9789811506024
024 7 _a10.1007/978-981-15-0602-4
_2doi
040 _aES-MaUEC
_bspa
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_dES-MaUEC
050 4 _aQH581.2
_b2019 EB
245 0 0 _aAutophagy: Biology and Diseases
_bBasic Science
_cedited by Zheng-Hong Qin.
250 _aFirst edition
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (XV, 727 páginas)
_b91 ilustraciones, 83 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v1206
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aHistory and current status of autophagy research -- Regulation of ATG and autophagy initiation -- Regulation of autophagy by mTOR signaling pathway -- AMPK and autophagy -- Beclin 1, Bcl-2 and autophagy -- TP53, TP53 target genes (DRAM, TIGAR) and autophagy -- Ca(2+) ion and autophagy -- Endoplasmic reticulum stress and autophagy -- Oxidative stress and autophagy -- Noncoding RNAs and atophagy -- Epigenetic regulation of autophagy -- Protein modification and autophagy activation -- Other molecular mechanisms regulating Autophagy -- The role of nanomaterials in autophagy -- Structural basis of autophagy regulatory proteins -- Autophagy and energy metabolism -- Autophagy and lipid metabolism -- Autophagy and the metabolism of misfolding protein -- Autophagy in mitochondrial quality control -- Chaperone-mediated autophagy -- Autophagy in reproduction -- Autophagy in development and differentiation -- Autophagy in normal stem cells and specialized cells -- Autophagy, aging and longevity -- Autophagy and the ubiquitin-proteasome system -- Immuno-signal and autophagy regulation -- Autophagy and the immune response -- Autophagy and immune tolerance -- Autophagy and cell survival and death -- Coordination of autophagy and other cellular activities.
520 3 _aThis book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.
988 _aPrimersemestre_2020_BiomedLife
650 7 _2embne
_aCitología
_9139477
700 1 _aQin, Zheng-Hong
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789811506017
776 0 8 _iPrinted edition:
_z9789811506031
776 0 8 _iPrinted edition:
_z9789811506048
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-0602-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
_n0
998 _b02/2020
_dz
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_zSI