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020			_a9789813296367
024	7		_a10.1007/978-981-32-9636-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP752 .M9 _b2019 EB
245	0	0	_aMyelin : _bBasic and Clinical Advances _cedited by Kazunori Sango, Junji Yamauchi, Toru Ogata, Keiichiro Susuki
250			_aFirst edition
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XI, 378 páginas) _b68 ilustraciones, 48 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1190
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPart 1. Myelination in neural development and regeneration -- 1. Cellular signal-regulated Schwann cell myelination and remyelination -- 2. Regulatory mechanism of peripheral nerve myelination by glutamate-induced signaling -- 3. Cytoskeletal signal-regulated oligodendrocyte myelination and remyelination -- 4. Activity-dependent myelination -- 5. Heterogeneity of oligodendrocytes and their precursor cells -- Part 2. Specialized structures along the myelinated nerve fibers -- 6. Functional domains in myelinated axons -- 7. Physiology of myelinated nerve conduction and pathophysiology of demyelination -- 8. Under the ECM dome: the physiological role of the perinodal extracellular matrix as an ion diffusion barrier -- 9. Oligodendrocyte physiology modulating axonal excitability and nerve conduction -- 10. Mitochondrial dynamics in physiology and pathology of myelinated axons -- 11. The role of sulfatides in axon-glia interactions -- 12. Structures and molecular composition of Schmidt-Lanterman incisures -- Part 3. Myelin pathology in the central nervous system -- 13. Pelizaeus-Merzbacher disease: molecular and cellular pathologies and associated phenotypes -- 14. Multiple sclerosis -- 15. Visualization of myelin for the diagnosis and treatment monitoring of multiple sclerosis -- 16. Roads to formation of normal myelin structure and pathological myelin structure -- 17. Therapeutic strategies for oligodendrocyte-mediated remyelination -- 18. Brain tumors of glial cell origin -- Part 4. Myelin pathology in the peripheral nervous system -- 19. Schwann cell and the pathogenesis of Charcot-Marie-Tooth disease -- 20. Guillain- Barré Syndrome -- 21. Chronic inflammatory demyelinating polyneuropathy -- 22. Schwann cells as crucial players in diabetic neuropathy -- 23. Drug-induced demyelinating neuropathies -- 24. Transthyretin amyloid neuropathy: the Schwann cell hypothesis.
520	3		_aThis book presents the latest exciting advances in understanding of the structure and function of myelin in the central and peripheral nervous systems under normal and pathological conditions. Readers will find state of the art information from the perspectives of both basic neuroscience and clinical neurology and neuropathology. Detailed attention is paid to the findings and implications of recent research on the myelin-forming glial cells such as oligodendrocytes and Schwann cells. The discussion of myelin pathology encompasses a wide range of diseases and conditions, including, for example, multiple sclerosis, Pelizaeus-Merzbacher disease, traumatic brain and spinal cord injuries, brain tumors of glial cell origin, Charcot-Marie-Tooth disease, immune-mediated neuropathy, and diabetic neuropathy. The authors comprise researchers at the cutting edge of biotechnology and experts in the diseases discussed. The clearly written text is supported by numerous high-quality light and electron microscopy, CT, and MR images.
988			_aPrimersemestre_2020_BiomedLife
650		7	_2embne _aLípidos _9142933
700	1		_aSango, Kazunori _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _985859
700	1		_aYamauchi, Junji _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _985860
700	1		_aOgata, Toru _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSusuki, Keiichiro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789813296350
776	0	8	_iPrinted edition: _z9789813296374
776	0	8	_iPrinted edition: _z9789813296381
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-32-9636-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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998			_b04/2020 _dz _eh _zSI