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020 _a9783030241001
024 7 _a10.1007/978-3-030-24100-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
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050 4 _aRC268.4
_b2019 EB
245 0 0 _aTranslational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics
_cedited by Erika Ruiz-Garcia, Horacio Astudillo-de la Vega.
250 _aFirst edition
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (X, 171 páginas)
_b19 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v1168
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aPreface -- Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer -- Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in Cancer -- Pharmaco-epigenomics: on the road of translation medicine -- Design and Implementing Pharmacogenomics Study in Cancer -- Onco-omics approaches and applications in Clinical Trials for Cancer patients -- Issues and Ethical Considerations in Pharmaco-oncogenomics -- Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools -- Inmuno-Oncology in the era of Personalized Medicine -- CAR T Cell and Personalized Medicine -- Oncobiome at the forefront of a novel molecular mechanism to understand the Microbiome and Cancer -- Nutrition, Cancer and Personalized Medicine -- Index.
520 3 _aThis book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient's specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory.
988 _aPrimersemestre_2020_BiomedLife
650 7 _2embne
_9273952
_aCáncer
_xAspectos genéticos
700 1 _aRuiz-Garcia, Erika
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAstudillo-de la Vega, Horacio
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783030240998
776 0 8 _iPrinted edition:
_z9783030241018
776 0 8 _iPrinted edition:
_z9783030241025
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-24100-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
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_n0
998 _b04/2020
_dz
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