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020 _a9789811398711
024 7 _a10.1007/978-981-13-9871-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRM409
_b2019 EB
245 0 0 _aAntibacterial Drug Discovery to Combat MDR
_bNatural Compounds, Nanotechnology and Novel Synthetic Sources
_cedited by Iqbal Ahmad, Shamim Ahmad, Kendra P. Rumbaugh.
250 _aFirst edition
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (XII, 680 páginas)
_b63 ilustraciones, 31 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aAntibacterial drug discovery: perspective insights -- Section A: The Challenge of Antibiotic Resistance and Tolerance -- Problematic Groups of Multidrug Resistant Bacteria and their Resistance Mechanisms -- Emergence and spread of multi-drug resistance in ocular bacterial pathogens: A current update -- Antibiotic resistance in Campylobacter jejuni: mechanism, status and public health significance -- Mechanisms of biofilm development, antibiotic resistance & tolerance and their role in persistent infections -- Developing in vivo infection models with MDR pathogens for evaluating compound efficacy -- Section B. New antibiotic drug discovery approaches and progress -- Endophytes: a hidden treasure of novel antimicrobial metabolites -- Alternative therapies to antibiotics to combat drug-resistant bacterial pathogens -- In silico molecular modeling: key technologies in the drug discovery process to combat multidrug resistance -- Computational approaches for antibacterial drug discovery -- Efflux pump inhibitors and their role in the reversal of drug resistance -- Medicinal plants as a reservoir of new structures for anti-infective compounds -- Essential oils: Potential application in disease management -- Exploration of soil resistome through a metagenomic approach -- Actinomycetes as a continued source of new antibacterial leads -- Are Ancient Remedies the New Answer to Fighting Infections? -- Section C. Alternative antibiotic resistance treatment strategies -- Pre and probiotics: Using functional foods in the fight against microbial resistance to antibiotics -- Combination of drugs: an effective approach for enhancing the efficacy of antibiotics to combat drug resistance -- Targeted delivery of antibiotics using microparticles to combat multi-drug-resistant tuberculosis -- Practical applications of bacteriophage therapy: biofilms to bedside -- Inhibition of Quorum sensing; prospects in disease control -- Approaches for disrupting tissue-associated biofilms -- Nanomedicine and nanoemulsion in increasing the availability of antibiotics -- Nanoparticles as new emerging antibacterials: potential and limitation -- Nanomaterials as a novel class of anti-infective agents that attenuate bacterial quorum sensing -- Nanoparticle-based drug delivery systems: promising approaches against bacterial infections -- Green synthesis of metal nanoparticles: characterization and their antibacterial efficacy.
520 3 _aThis book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
988 _aPrimersemestre_2020_BiomedLife
650 7 _2embne
_9138527
_aAntibióticos
700 1 _aAhmad, Iqbal
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAhmad, Shamim
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRumbaugh, Kendra P
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_948578
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789811398704
776 0 8 _iPrinted edition:
_z9789811398728
776 0 8 _iPrinted edition:
_z9789811398735
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-9871-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
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_n0
998 _b03/2020
_dz
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