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008			191105s2019 xxua o |||| 0|eng d
020			_a9781493998029
024	7		_a10.1007/978-1-4939-9802-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP321 _b2019 EB
245	0	0	_aOmics Approaches to Understanding Muscle Biology _cedited by Jatin George Burniston, Yi-Wen Chen.
250			_aFirst edition
264		1	_aNew York _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VII, 217 páginas) _b35 ilustraciones, 32 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMethods in Physiology
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPart I: Genomic and Epi-genomic -- 1) GWAS/muscle function and diseases (by Eric Hoffman) -- 2) Whole genome and whole exon sequencing/muscle disorders (by Silvère van der Maarel and Richard Lemmers) -- 3) Epi-genome approaches/muscle regeneration (by Vittorio Sartorelli) -- Part II: Transcriptomic -- 4) RNA profiling (by Yi-Wen Chen, confirmed) -- 5) miRNA profiling (by Alyson Fiorillo) -- 6) Single cell profiling in muscle (byPier Lorenzo Puri) -- 7) Statistics and bioinformatics (by Heather Gordish) -- Part III: Proteomic -- 8). Proteome profiling of human/ clinical samples - i.e. necessarily label-free techniques (by Lawrence Mandarino) -- 9) Proteome profiling of cell and animal models - i.e. label techniques such as SILAC (by Matthias Mann OR SILAM with JR Yates III) -- 10) Global analysis of post-translational modifications (by David E James) -- 11) Proteome dynamics - synthesis and degradation on a proteome wide scale (by Jatin Burniston, confirmed) -- Part IV: Metabolomic -- 12) Non-targeted metabolomics using mass spectrometry (by Charles Burant).
520	3		_aThis book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses. Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.
988			_aPrimersemestre_2020_BiomedLife
650		7	_2embne _9210898 _aMúsculos _xFisiología
700	1		_aBurniston, Jatin George _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aChen, Yi-Wen _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781493998012
776	0	8	_iPrinted edition: _z9781493998036
776	0	8	_iPrinted edition: _z9781493998043
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-9802-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2020 _dz _eh _zSI