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020			_a9783030231583
024	7		_a10.1007/978-3-030-23158-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP552 .H43 _b 2019 EB
245	0	0	_aHeat Shock Protein 90 in Human Diseases and Disorders _cedited by Alexzander A. A. Asea, Punit Kaur.
250			_aFirst edition
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XI, 607 páginas) _b102 ilustraciones, 73 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aHeat Shock Proteins _x1877-1246 _v19
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aSECTION I: ONCOGENIC ASPECTS OF HSP90 -- Chapter 1. Regulatory Roles of HSP90-rich Extracellular Vesicles -- Chapter 2. HSP90-Based Heterocomplex as Essential Regulator for Cancer Disease -- Chapter 3. Therapeutic Potential of Heat Shock Protein 90 Inhibitors in Colorectal Cancer -- Chapter 4. Hsp90 in the Migration of Primordial Germ Cells: A Model to Study Long-Distance Cell Migration and Perhaps Cancer? -- Chapter 5. Role of Heat Shock Protein 90 in Mammary Tumorigenesis -- Chapter 6. Role of HSP90 Inhibitors in the Treatment of Cancer -- Chapter 7. p53-HSP90 Axis in Human Cancer -- Chapter 8. HSP90 and its Inhibitors for Cancer Therapy: Use of Nano-delivery System to Improve its Clinical Application -- Chapter 9. Hsp90 is a Pivotal Player in Retinal Disease and Cancer -- Chapter 10. Targeting Hsp-90 Related Disease Entities for Therapeutic Development -- Chapter 11. HSP90: A Key Player in Metal-Induced Carcinogenesis? -- Section II: Biomolecular Aspects of HSP90 -- Chapter 12. Hsp90 and its Role in Heme-Maturation of Client Proteins: Implications for Human Diseases -- Chapter 13. Moonlighting Functions of Heat Shock Protein 90 -- Chapter 14. Hsp90 as a Member of Dicarboxylate Clamp TPR Protein Interaction Network: Implication in Human Diseases and Prospect as a Drug Target -- Chapter 15. 'Complex World' of Hsp90 Co-chaperone R2TP -- Chapter 16. Functions of SGT1, a Co-chaperone -- Chapter 17. Sti1/Hop Plays a Pivotal Role in Hsp90 Regulation beyond Bridging Hsp70 -- Section III: HSP90 in Natural Products Development.-Chapter 18. Hsp90: A Target for Susceptibilities and Substitutions in Biotechnological and Medicinal Application -- Chapter 19. Screening Technique for Heat Shock Protein 90 Inhibitors from Natural Products -- Chapter 20. Therapeutic Effects and Related Molecular Mechanisms of Celastrol, a Triterpenoid Natural Compound and Novel HSP90 Inhibitor Extracted from Plants of the Celastraceae Family -- Section IV: Clinical Aspects of HSP90 -- Chapter 21. Hsp90 Chaperone in Disease -- Chapter 22. Theranostic Implications of Heat Shock Proteins in Idiopathic Pulmonary Fibrosis -- Chapter 23. Heat Shock Protein 90 and Reproduction in Female Animals: Ovary, Oocyte and Early Embryo -- Chapter 24. Heat Shock Protein 90 in Severe Trauma -- Chapter 25. HSP90 - Is there an Unknown Role in Pain Neurobiology -- Chapter 26. Heat Shock Protein 90 in Kidney Stone Disease -- Chapter 27. HSP90 et al. - Chaperome and Proteostasis Deregulation in Human Disease.
520	3		_aThe book Heat Shock Protein 90 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP90. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, previously unknown signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding Oncogenic Aspects of HSP90; Section II, focuses on Bimolecular Aspects of HSP90; Section III, emphasizes and HSP90 in Natural Products Development and Section IV; give the most up to date reviews on Clinical Aspects of HSP90. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Natural Products, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
988			_aPrimersemestre_2020_BiomedLife
650		7	_aProteínas de choque térmico _2embne _9160151
700	1		_aAsea, Alexzander A. A. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _993800
700	1		_aKaur, Punit _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _993802
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783030231576
776	0	8	_iPrinted edition: _z9783030231590
776	0	8	_iPrinted edition: _z9783030231606
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-23158-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2020 _dz _eh _zSI