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020 _a9789811505577
024 7 _a10.1007/978-981-15-0557-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP535.Z6
_b2019 EB
245 0 0 _aZinc Signaling
_cedited by Toshiyuki Fukada, Taiho Kambe.
250 _aSecond edition
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (VIII, 413 páginas)
_b70 ilustraciones, 56 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _a1 Opening The Second Era of Zinc Signaling study -- 2 Regulation of cellular zinc ions and their signalling functions -- 3 Zinc transporter proteins-A review and a new view from biochemistry -- 4 The Metallothionein-Zinc Landscape: How It Shapes Antimicrobial Immunity -- 5 Role of Zinc signaling in mast cell, basophil, T cell, and B cell -- 6 The role of Zinc signaling in reproduction -- 7 Zinc Signaling in Skeletal Muscle -- 8 Zinc Signaling in Aging Heart Function -- 9 Zinc signaling in the life and death of neurons -- 10 Possible therapeutic roles of metallothionein-3 and zinc in endosome-autophagosome-lysosomal pathway (EALP) dysfunction in astrocytes -- 11 Zinc in neurodegeneration -- 12 Role of Zinc Transporters in Type 2 Diabetes and Obesity -- 13 Zinc Signals in Immunology -- 14 Zinc Signals in Inflammation -- 15 Zinc transporters and zinc signaling in skin formation and diseases -- 16 Post-translational mechanisms of zinc signalling in cancer -- 17 Zinc Signaling (Zinc'in) in Intestinal function -- 18 In Situ Imaging of Zinc with Synthetic Fluorescent Probes -- 19 Zinc Signals in biology.
520 3 _aThis book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.
988 _aPrimersemestre_2020_BiomedLife
650 7 _2embne
_9672504
_aCinc
_xEfectos fisiológicos
700 1 _aFukada, Toshiyuki
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_985878
700 1 _aKambe, Taiho
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_985879
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789811505560
776 0 8 _iPrinted edition:
_z9789811505584
776 0 8 _iPrinted edition:
_z9789811505591
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-0557-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
_n0
998 _b03/2020
_dz
_ek
_zSI