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020 _a9783030339623
024 7 _a10.1007/978-3-030-33962-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aTA418.9.N35
_b2020 EB
245 0 0 _aInteraction of Nanomaterials with the Immune System
_cedited by James C. Bonner, Jared M. Brown.
250 _aFirst edition
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2020
300 _a1 recurso en línea (X, 223 páginas)
_b16 ilustraciones, 5 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMolecular and Integrative Toxicology
_x2168-4219
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aOverview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure -- Engineered nanomaterials: synthesis, characterization, uses and exposure -- Impact of nanomaterials on barrier function -- Complement activation and inflammation -- Macrophage function and phagocytosis -- Mast cells -- Impact on dendritic cell - lymphocyte function -- Impact on host pathogen response and microbiome -- Allergy/autoimmunity -- Pre-existing allergic or bacterial-induced lung disease -- Nanomaterial effects on viral infection -- Immunotoxicity and carcinogenesis -- In vivo animal models (nude mice, transgenic models) -- In vitro cell culture models -- In silico computational modeling -- Summary of mechanisms of immune modulation. .
520 3 _aThis book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs. .
988 _aPrimersemestre_2020_BiomedLife
650 7 _2embne
_9158454
_aMateriales nanoestructurados
700 1 _aBonner, James C
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBrown, Jared M
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_971407
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783030339616
776 0 8 _iPrinted edition:
_z9783030339630
776 0 8 _iPrinted edition:
_z9783030339647
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-33962-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
_n0
998 _b03/2020
_dz
_ek
_zSI