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020			_a9783030273781
024	7		_a10.1007/978-3-030-27378-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRE551 _b2019 EB
245	0	0	_aRetinal Degenerative Diseases : _bMechanisms and Experimental Therapy _cedited by Catherine Bowes Rickman, Christian Grimm, Robert E. Anderson, John D. Ash, Matthew M. LaVail, Joe G. Hollyfield.
250			_aFirst edition
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XVI, 596 páginas) _b132 ilustraciones, 86 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1185
490	0		_aBiomedical and Life Sciences (Springer-11642)
520	3		_aThis book contains the proceedings of the XVIII International Symposium on Retinal Degeneration (RD2018). A majority of those who spoke and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium focused on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the "best" and "most important" meetings in the field. The volume presents representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. While advances in these areas of retinal degenerations were described, there will be many new topics that either are in their infancy or did not exist at the time of the last RD Symposium, RD2016. These include the role of inflammation and immunity, as well as other basic mechanisms, in age-related macular degeneration, several new aspects of gene therapy, and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those were reported at the RD2016 meeting and included in the current volume. We anticipate the excitement of those working in the field and those afflicted with retinal degenerations is reflected in the volume. .
988			_aPrimersemestre_2020_BiomedLife
650		7	_2embne _9190667 _aRetina _xEnfermedades
700	1		_aBowes Rickman, Catherine _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _984495
700	1		_aGrimm, Christian _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _98523
700	1		_aAnderson, Robert E. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _984493
700	1		_aAsh, John _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _910139
700	1		_aLaVail, Matthew M. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _984494
700	1		_aHollyfield, Joe G. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _984492
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783030273774
776	0	8	_iPrinted edition: _z9783030273798
776	0	8	_iPrinted edition: _z9783030273804
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-27378-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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998			_b05/2020 _dz _ea _zSI