000			03385nam a22003975i 4500
988			_aSpringer_BiomedLife_2019
999			_c116796 _d116796 _x1
001			116796
003			ES-MaUEC
005			20230104140202.0
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007			cr nn nnnaamaa
008			191010s2019 gw | s |||| 0|eng d
020			_a9783030267803
024	7		_a10.1007/978-3-030-26780-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH671 _b2019 EB
245	0	0	_aFerroptosis in Health and Disease _cedited by Daolin Tang.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VI, 324 páginas) _b36 ilustraciones, 35 ilustraciones
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aLipid metabolism and ferroptosis -- 2. Iron metabolism and ferroptosis -- 3. Regulation and Function of Autophagy During Ferroptosis -- 4.Heat Shock Proteins: Endogenous Modulators of Ferroptosis -- 5. Biological Aspects of Endoplasmic Reticulum Stress in Ferroptosis -- 6. Gpx4 in ferroptosis -- 7. ACSL4 as the First Reliable Biomarker of Ferroptosis Under Pathophysiological Conditions -- 8. Regulation of Ferroptosis by MicroRNAs -- 9. Ferroptosis in Cardiovascular Disease -- 10. Ferroptosis in Nervous System Diseases -- 11. Regulation of Ferroptosis Through the Cysteine-Glutathione Redox Axis -- 12. Iron-Sulfur Cluster Metabolism Impacts Iron Homeostasis, Ferroptosis Sensitivity, and Human Disease -- 13. Ferroptosis in Liver Disease -- 14. p53 and Ferroptosis -- 15. Ferroptosis in Hemolytic Disorders -- 16. Lipoxygenase in Ferroptosis -- 17. Ferroptosis in Cancer Disease -- 18. Ferroptosis in Cancer Therapy.
520	3		_aThis book sheds new light on ferroptosis, as an only recently recognised form of regulated cell death. Its respective chapters address the numerous implications that ferroptosis can have for virtually all aspects of metabolism. They also share insights on the morphological characterisation of ferroptosis and highlight the different pathways of induction. Accordingly, the book offers a unique perspective on a mechanism that is involved in a multitude of pathologies, including cancer cell death, neurotoxicity, neurodegenerative diseases, acute renal failure, drug-induced hepatotoxicity, tissue ischemia/reperfusion injury, and T cell immunity. Readers will learn in which cell types this form of regulated cell death is likely to occur, and how it can be pharmacologically influenced, making the book a fascinating and informative read not only for scientists working in cell biology, but also for clinicians in the field of cancer research. .
650		7	_2embne _9157983 _aApoptosis
700	1		_aTang, Daolin _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030267797
776	0	8	_iPrinted edition: _z9783030267810
776	0	8	_iPrinted edition: _z9783030267827
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-26780-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI