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020 _a9789811391095
024 7 _a10.1007/978-981-13-9109-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRB53
_b2019 EB
245 0 0 _aUrine :
_bPromising Biomarker Source for Early Disease Detection
_cedited by Youhe Gao.
250 _a1st ed. 2019.
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (VI, 244 páginas)
_b51 ilustraciones, 37 ilustraciones
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aUrine is not a human waste but a medical treasure -- Human Urine proteome: a powerful source for clinical research -- Comparison of urinary proteomes among three animal models -- Urimen, a membrane that store urinary components for largescale biomarker study -- Post-translation modifications of human urine -- Application of Peptide Level and Post translational Modifications to Integrative Analyses in Proteomics -- Urinary Protein Biomarker Database 2.0: a literature-curated database for protein biomarkers in urine -- Urine glucose levels are disordered before blood glucose level increase was observed in Zucker diabetic fatty rats -- Cancer Biomarker Discovery in Urine of Walker 256 Tumor-bearing Models -- Candidate Urinary Biomarker Discovery in Gliomas -- Changes in the Urinary Proteome in a Patient-Derived Xenograft (PDX) Nude Mouse Model of Colorectal Tumor -- Urine is an ideal biomarker resource in early detecting neurodegenerative diseases -- Urinary proteome biomarkers for early detection of respiratory diseases -- Application of urine proteome in cardiac diseases biomarker discovery -- Changes of Urinary Proteins in infectious disease models -- The application of urinary proteomics in early detection of digestive diseases -- Serial changes of urinary proteome in animal models of renal diseases -- Effects of extrinsic factors on the urinary proteome -- Exhaled Breath: Another Biomarker Source that Complementary to Urine -- Tears: potential window for monitoring systemic conditions.
520 3 _aThis book demonstrates the potential of urine as a biomarker resource for early disease detection, covering the related theory, strategies, tools and findings. Biomarkers are measurable changes associated with diseases. Blood, as a critical part of its internal environment, is closely monitored and controlled by the body to maintain homeostasis, especially in the early stages of diseases. In contrast, urine, as a form of waste excreted by the body, collects a variety of substance changes. Accordingly, urine can offer an ideal resource for early biomarker discovery. In addition, urine is more stable than blood in vitro, and is easy to store and analyze. The book discusses exciting preliminary applications of urine biomarkers for diseases affecting major biological systems. Its main goal is to make scientists, clinicians and medical companies aware of this important, exciting, undeveloped, and profitable field.
650 7 _2embne
_9192364
_aOrina
_xAnálisis
700 1 _aGao, Youhe
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_994278
776 0 8 _iPrinted edition:
_z9789811391088
776 0 8 _iPrinted edition:
_z9789811391101
776 0 8 _iPrinted edition:
_z9789811391118
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-9109-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_cm
_dz
_feng
_ggw
_h0
_b01/2020
_ek
_zSI