000			03446nam a22004095i 4500
988			_aSpringer_BiomedLife_2019
999			_c116750 _d116750 _x1
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005			20230104140150.0
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008			190913s2019 gw | s |||| 0|eng d
020			_a9783030236298
024	7		_a10.1007/978-3-030-23629-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC267 _b2019 EB
245	0	4	_aThe Drosophila Model in Cancer _cedited by Wu-Min Deng.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VI, 250 páginas) _b56 ilustraciones, 55 ilustraciones
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1167
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPrelims -- Drosophila model in cancer: an introduction -- Using Drosophila models and tools to understand the mechanisms of novel human cancer driver gene function -- The initial stage of tumorigenesis in Drosophila epithelial tissuesi -- Drosophila models of cell polarity and cell competition in tumourigenesis -- Two sides of the same coin - compensatory proliferation in regeneration and cancer -- P53 and apoptosis in the Drosophila model -- Autophagy and tumorigenesis in Drosophila -- Filling the gaps among obesity, the CDK8 module, and uterine tumors using Drosophila -- MicroRNAs in Drosophila cancer models -- Cancer Stem Cells and Stem Cell Tumors in Drosophila -- Drosophila as a model for tumor-induced organ wasting -- Drosophila melanogaster as a model system for human glioblastomas -- What Drosophila Can Teach Us About Radiation Biology of Human Cancers -- Drosophila based cancer drug discovery frameworkIn -- Index.
520	3		_aThis volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression. Readers will discover the beauty of the fly model's genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use. This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems. This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.
650		7	_2embne _aCáncer _xInvestigación _9182523
700	1		_aDeng, Wu-Min _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030236281
776	0	8	_iPrinted edition: _z9783030236304
776	0	8	_iPrinted edition: _z9783030236311
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-23629-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI