| 000 | 03841nam a2200433 i 4500 | ||
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| 988 | _aSpringer_BiomedLife_2019 | ||
| 999 |
_c115934 _d115934 _x1 |
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| 001 | 115934 | ||
| 003 | ESmaUEC | ||
| 005 | 20230110040243.0 | ||
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| 007 | cr nn nnnaamaa | ||
| 008 | 190731s2019 si | s |||| 0|eng d | ||
| 020 | _a9789811362606 | ||
| 024 | 7 |
_a10.1007/978-981-13-6260-6 _2doi |
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| 040 |
_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC |
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| 050 | 4 |
_aQP603.A35 _b2019 EB |
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| 245 | 0 | 0 |
_aAldehyde Dehydrogenases : _bFrom Alcohol Metabolism to Human Health and Precision Medicine _cedited by Jun Ren, Yingmei Zhang, Junbo Ge. |
| 250 | _a1st ed. 2019. | ||
| 264 | 1 |
_aSingapore _bSpringer International Publishing _c2019 |
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| 300 |
_a1 recurso en línea (XX, 253 páginas) _b 27 ilustraciones, 20 ilustraciones a color |
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| 336 |
_aTexto _btxt _2rdacontent |
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| 337 |
_2rdamedia _aelectrónico _bc |
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| 338 |
_2rdacarrier _arecurso electrónico _bcr |
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| 347 |
_atext file _bPDF |
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| 490 | 0 |
_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1193 |
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| 490 | 0 | _aBiomedical and Life Sciences (Springer-11642) | |
| 505 | 0 | _a1. Role of alcohol oxidative metabolism in its cardiovascular and autonomic effects -- 2. Environmental aldehyde sources and the health implications of exposure -- 3. ALDH2 and cardiovascular disease -- 4. Aldehyde dehydrogenases: From alcohol metabolism to human health and precision medicine -- 5. Aldehyde dehydrogenase 2 and heart Failure -- 6. Mitochondrial aldehyde dehydrogenase in myocardial ischemic and ischemia-reperfusion injury -- 7. East Asian variant aldehyde dehydrogenase 2 genotype (ALDH2*2*) contributes to coronary artery spasm and acute myocardial infarction -- 8. Aldehyde dehydrogenases genetic polymorphism and obesity: from genomics to behavior and health -- 9. Aldehyde dehydrogenase (ALDH) 2 in diabetic heart diseases -- 10. The role of ALDH2 in sepsis and the to-be-discovered mechanisms -- 11. ALDH2 and stroke -- 12. ALDH2 and hypertension -- 13. ALDH2 and cancer therapy -- 14. ALDH2 polymorphism and ethanol consumption: A genetic-environmental interaction in carcinogenesis -- 15. ALDH2 and aging. | |
| 520 | 3 | _aThis volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes. It thoroughly reviews the roles of ALDH family in alcohol metabolism, as well as recent findings of their emerging roles in a variety of human pathologies such as cardiovascular diseases, diabetes, obesity, stroke, cancer, liver diseases and kidney diseases. Delicate contribution of ALDH enzymes in the therapeutics against chronic diseases is also discussed. It demonstrates the unique value of targeting genetic polymorphism in ALDH enzymes in personalized medicine. The book will appeal to scientists, physicians, graduate and professional students in the fields of ALDH enzymes, alcohol metabolism, cardiometabolic and other chronic diseases. Pharmaceutical and other companies developing new tools for cardiometabolic and chronic diseases treatment will also find this a valuable resource. | |
| 650 | 7 |
_2embne _9671805 _aAldehído deshidrogenasa |
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| 700 | 1 |
_aRen, Jun _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aZhang, Yingmei _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aGe, Junbo _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 776 | 0 | 8 |
_iPrinted edition: _z9789811362590 |
| 776 | 0 | 8 |
_iPrinted edition: _z9789811362613 |
| 776 | 0 | 8 |
_iPrinted edition: _z9789811362620 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-6260-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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_2lcc _cLE |
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| 998 |
_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI |
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