000			03948nam a2200409 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115911 _d115911 _x1
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003			ESmaUEC
005			20230104140135.0
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008			190722s2019 gw | s |||| 0|eng d
020			_a9783030217372
024	7		_a10.1007/978-3-030-21737-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP801.C27 _b2019 EB
245	0	0	_aRecent Advances in Cannabinoid Physiology and Pathology _cedited by Anna N. Bukiya.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (IX, 167 páginas) _b 16 ilustraciones, 10 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1162
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPrelims -- Introduction -- Endocannabinoid System Components: Overview and Tissue Distribution -- Physiology of the Endocannabinoid System During Development -- Cannabinoid Interactions With Proteins: Insights From Structural Studies -- Cannabinoid Signaling in Cancer -- Cannabinoids and Cardiovascular System -- Endocannabinoid System and Alcohol Abuse Disorders -- Genetic factors in Cannabinoid Use and Dependence -- Pharmacology of Medical Cannabis -- Index.
520	3		_aThis book comprehensively covers modern topics in cannabinoid research and medicinal use. The chapters span topics from the role of endocannabinoid system in embryonic and fetal development to cardiovascular disease, cancer, drug abuse and cutting-edge therapeutic applications. The content is presented at different levels of resolution. First, following an introduction into cannabinoid system components, readers are immersed into cannabinoid chemistry with a systematic overview of structural data that describe cannabinoid complexes with proteins at the atomic resolution. The remaining chapters capitalize on these interactions. They describe the cannabinoid role during embryonic, fetal, and adolescent development, in the cardiovascular system, cancer progression, and development of alcohol use disorders. Next, the topic of illicit marijuana use and abuse is discussed with an emphasis on possible genetic factors that may play a role in dependence. The book concludes with the most integrative level. It covers promising pharmacological leads in medicinal use of cannabimimetics to treat pain, epilepsy, and neurodegenerative disorders. The book brings together contributions from researchers and clinical scientists at different career stages. While some chapters are presented by well-recognized names, others are written by young investigators emerging in the field of cannabinoid research and medicinal use. The book will be of interest to audiences from biological/chemical disciplines with keen interest in the physiological effects of cannabis. The text quickly introduces the reader to the multi-faceted roles played by endogenous, phyto- and synthetic cannabinoids in health, disease, and modern drug development. Reader will gain insight into the current state of popular but still controversial topic of cannabinoids.
650		7	_2embne _aCannabis _xUso terapéutico _9262120
700	1		_aBukiya, Anna N _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030217365
776	0	8	_iPrinted edition: _z9783030217389
776	0	8	_iPrinted edition: _z9783030217396
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-21737-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI