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020 _a9789811378447
024 7 _a10.1007/978-981-13-7844-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP552.P4
_b2019 EB
100 1 _aRamachandran, Saravanan
_eautor
_9671864
245 1 0 _aZebrafish: A Model for Marine Peptide Based Drug Screening
_cby Saravanan Ramachandran, Senthilkumar Rajagopal.
250 _a1st ed. 2019.
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (XI, 73 páginas)
_b 39 ilustraciones, 29 ilustraciones a color
336 _aTexto
_btxt
_2rdacontent
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aChapter 1. Biomedical importance of marine peptides/toxins -- Chapter 2. Toxicity of peptides in Zebrafish embryos -- Chapter 3. Teratogenic activity of toxins in Zebrafish model -- Chapter 4. Anticancer properties marine peptides/toxins using Zebrafish model -- Chapter 5. Protective effect of marine peptides/toxins in CVD using Zebrafish model.
520 3 _aThis book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
650 7 _2embne
_9146243
_aPéptidos
700 1 _aRajagopal, Senthilkumar.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9668852
776 0 8 _iPrinted edition:
_z9789811378430
776 0 8 _iPrinted edition:
_z9789811378454
776 0 8 _iPrinted edition:
_z9789811378461
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-7844-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_cm
_dz
_feng
_ggw
_h0
_b01/2020
_ek
_zSI