000			04844nam a2200457 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115881 _d115881 _x1
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003			ESmaUEC
005			20230110040241.0
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007			cr nn nnnaamaa
008			190809s2019 si | s |||| 0|eng d
020			_a9789811388712
024	7		_a10.1007/978-981-13-8871-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC903.9 _b2019 EB
245	0	0	_aRenal fibrosis : _bmechanisms and therapies _cedited by Bi-Cheng Liu, Hui-Yao Lan, Lin-Li Lv
250			_aFirst edition
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XVI, 709 páginas) _b63 ilustraciones, 55 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1165
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPrevalence and burden of chronic kidney disease -- Pathomorphism and evaluation of renal fibrosis -- Endothelial cells and renal fibrosis -- Mesangial cells and renal fibrosis -- Podocyte injury and glomerular sclerosis -- Tubular epithelial cell injury and renal fibrosis -- Monocyte-macrophages and renal fibrosis -- Pericytes and renal fibrosis -- Myofibroblast: Origin and regulation in renal fibrosis -- Mitochondrial lesion and renal fibrosis -- Metabolic nuclear receptors and renal fibrosis -- Role of renin angiotensin system in renal fibrosis -- Role of aldosterone in renal fibrosis -- TGF-β1 and renal fibrosis -- Connective tissue growth factor and renal fibrosis -- Lipid metabolism disorder and renal fibrosis -- Renal interstitial lymphangiogenesis in renal fibrosis -- Cell apoptosis and autophagy in renal fibrosis -- Pyroptosis and renal fibrosis -- Cell cycle arrest and renal fibrosis -- Inflammatory mediators and renal fibrosis -- Role of inflammasome in chronic kidney disease -- Oxidative stress and renal fibrosis -- Hypoxia and renal tubulointerstitial fibrosis -- Proteinuria and progression of chronic kidney disease -- Hypertension and renal fibrosis -- Diabetic Kidney disease and renal fibrosis -- Chronic allograft nephropathy and renal fibrosis -- Polycystic kidney disease and renal fibrosis -- Acute kidney injury and renal fibrosis -- Senescence and renal fibrosis -- Urinary biomarkers of renal fibrosis -- New therapies for the treatment of renal fibrosis. .
520	3		_aThis book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.
650		7	_2embne _9168885 _aRiñones _xEnfermedades _xTratamiento
650		7	_2embne _aRiñones _xFibrosis
650		7	_2embne _aAparato urinario _xEnfermedades _9189633
700	1		_aLiu, Bi-Cheng _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLan, Hui-Yao _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLv, Lin-Li _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811388705
776	0	8	_iPrinted edition: _z9789811388729
776	0	8	_iPrinted edition: _z9789811388736
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-8871-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _eel _zSI