000			04826nam a2200409 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115876 _d115876 _x1
001			115876
003			ESmaUEC
005			20230104140125.0
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007			cr nn nnnaamaa
008			190709s2019 gw | s |||| 0|eng d
020			_a9783030039523
024	7		_a10.1007/978-3-030-03952-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP552.H43 _b2019 EB
245	0	0	_aHeat Shock Proteins in Signaling Pathways _cedited by Alexzander A. A. Asea, Punit Kaur.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XI, 482 páginas) _b 63 ilustraciones, 41 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aHeat Shock Proteins _x1877-1246 _v17
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aThiol-based Redox Signaling: Impacts on Molecular Chaperones and Cellular Proteostasis -- Heat Shock Proteins (HSP) in Stress-Related Inflammatory Diseases -- Heat Shock Response and Metabolism in Skeletal Muscle -- Temperature Stress and Redox Homeostasis: The Synergistic Network of Redox and Chaperone System in Response to Stress in Plants -- Dynamics of Heat Shock Proteins in Immunity and Aging -- Heat Shock Proteins, Exercise and Inflammation -- Heat Shock Proteins and Alarmins in Autoimmunity -- HO-1/Hsp32 and Cardiac Stress Signaling -- Targeting Heat Shock Proteins in Multiple Myeloma -- IER5 is a p53-Reguated Activator of HSF1 that Contributes to Promotion of Cancer -- Heat Shock Proteins in Digestive Tract Cancer: Molecular Mechanism and Therapeutic Potential -- The Role of Heat Shock Protein 90 in Regulating Downstream Signal Transduction Cascades -- Extracellular Hsp90a versus Intracellular Hsp90b in Wound Healing and Cancer -- Regulation of Calcineurin Signaling through Blocking of the Chaperone Function of Hsp90 by HDAC Inhibitors -- Signaling Functions of Extracellular Hsp90 (eHsp90) in Cancer Metastasis -- The Role of the Molecular Chaperones Hsp70 and Hsp90 in the DNA Damage Response -- Heat Shock Protein 90 Inhibitors in Lung Cancer Therapy -- Hsp90 Inhibitors Blocking Multiple Oncogenic Signaling Pathways for the Treatment of Cancer -- Diverse Roles of Heat Shock Proteins in Immune Activation and Tolerance: A Comprehensive Review of Mechanisms and Therapeutic Relevance -- The Role of Heat Shock Proteins on Neuromuscular Disorders/Neuronal Differentiation -- Heat Shock Proteins in Neural Signaling: Implications in Health and Disease -- Cytosolic Heat Shock Protein 90 in Plant Hormone and Environmental Stress Response.
520	3		_aThis edited volume offers an insightful overview of contemporary research on signaling pathways. These signaling processes are the comprehensive mechanisms by which all cellular organisms communicate internally and externally with their microenvironment. The volume is focused on heat shock proteins (HSP), which are uniquely involved in a number of critical signaling pathways. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. The knowledge gained from better understanding these mechanisms can help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
650		7	_aProteínas de choque térmico _2embne _9160151
700	1		_aAsea, Alexzander A. A. _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _993800
700	1		_aKaur, Punit _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _993802
776	0	8	_iPrinted edition: _z9783030039516
776	0	8	_iPrinted edition: _z9783030039530
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-03952-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI