000			03247nam a2200409 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115851 _d115851 _x1
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005			20230104140119.0
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008			190827s2019 si | s |||| 0|eng d
020			_a9789811395895
024	7		_a10.1007/978-981-13-9589-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP535.F4 _b2019 EB
245	0	0	_aBrain Iron Metabolism and CNS Diseases _cedited by Yan-Zhong Chang.
250			_a1st ed. 2019.
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (IX, 194 páginas) _b 6 ilustraciones, 5 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1173
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aBrain Iron Metabolism and CNS Diseases -- Cellular iron metabolism and regulation -- Brain iron metabolism and regulation -- Iron pathophysiology in Parkinson diseases -- Iron pathophysiology in Alzheimer's diseases -- Iron pathophysiology in stroke -- Iron pathophysiology in Friedreich's ataxia -- Iron pathophysiology in amyotrophic lateral sclerosis -- Iron pathophysiology in Neurodegenerative with Brain Iron Accumulation -- Diagnostics and treatments of iron-related CNS diseases.
520	3		_aThis book focuses on advances in our understanding of the regulatory mechanisms of brain iron uptake, iron homeostasis and iron metabolism in the pathophysiology and pharmacology of CNS disease models. Dysregulation of brain iron homeostasis can lead to severe pathological changes in the neural system. Iron deficiency can slow down the development of the neural system and cause language and motion disorders, while iron overload is closely related to neurodegenerative diseases. Although some current books include chapters on iron metabolism and certain neurodegenerative diseases, this is the first systematic summary of the latest discoveries regarding brain iron metabolism and CNS diseases. By providing novel and thought-provoking insights into the mechanisms and physiological significance of brain iron metabolism and related diseases, the book stimulates further new research directions. It helps graduate students and researchers gain an overall picture of brain iron metabolism and the pathogenesis of neurodegenerative diseases, and also offers pharmaceutical companies inspiration for new treatment strategies for CNS diseases.
650		7	_2embne _9671803 _aHierro en el organismo
700	1		_aChang, Yan-Zhong _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811395888
776	0	8	_iPrinted edition: _z9789811395901
776	0	8	_iPrinted edition: _z9789811395918
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-9589-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI