000			03071nam a2200433 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115848 _d115848 _x1
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003			ESmaUEC
005			20230104140118.0
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008			190903s2019 gw | s |||| 0|eng d
020			_a9783030310530
024	7		_a10.1007/978-3-030-31053-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR185.8.F33 _b2019 EB
245	0	0	_aFc Mediated Activity of Antibodies : _bStructural and Functional Diversity _cedited by Jeffrey V. Ravetch, Falk Nimmerjahn.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VII, 150 páginas) _b 14 ilustraciones, 12 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v423
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aIgG Fc receptors: evolutionary considerations -- Role of FcgRs in Antibody Based Cancer Therapy -- Anti-inflammatory Activity of IgG-Fc -- IgG Fc glycosylation in human immunity -- IgE Glycosylation in Health and Disease -- Immune Complex Vaccination -- Fc receptors in anti-microbial protection.
520	3		_aThis volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
650		7	_2embne _aInmunología _9138330
650		7	_2embne _aProteínas _9139861
700	1		_aRavetch, Jeffrey V _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aNimmerjahn, Falk _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt _984739
776	0	8	_iPrinted edition: _z9783030310523
776	0	8	_iPrinted edition: _z9783030310547
776	0	8	_iPrinted edition: _z9783030310554
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-31053-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI