000			04350nam a2200421 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115843 _d115843 _x1
001			115843
003			ESmaUEC
005			20230110040239.0
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007			cr nn nnnaamaa
008			190610s2019 si | s |||| 0|eng d
020			_a9789811358951
024	7		_a10.1007/978-981-13-5895-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP321 _b2019 EB
245	0	0	_aSmooth Muscle Spontaneous Activity : _bPhysiological and Pathological Modulation _cedited by Hikaru Hashitani, Richard J. Lang.
250			_a1st ed. 2019.
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XIX, 427 páginas) _b 109 ilustraciones, 63 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1124
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPART I: Gastrointestinal tract -- Phasic muscle -- Spontaneous electrical activity and rhythmicity in gastrointestinal smooth muscles -- Tonic muscle (Sphincters) -- Generation of tone by gastrointestinal sphincters -- PART II: Urinary tract -- Renal pelvis -- Pacemaker mechanisms driving pyeloureteric peristalsis: modulatory role of interstitial cells -- Ureter -- Excitation-contraction coupling in ureteric smooth muscle: mechanisms driving ureteric peristalsis -- Urinary Bladder -- Spontaneous activity and the urinary bladder -- Urethra -- Spontaneous activity in urethral smooth muscle -- PART III: Reproductive organs -- Corporal tissue -- Ion channels and intracellular calcium signalling in corpus cavernosum -- Prostate -- Generation and regulation of spontaneous contractions in the prostate gland -- Seminal vesicle -- Mucosa-dependent, stretch-sensitive spontaneous activity in seminal vesicle -- Uterus -- The myometrium - from excitation to contractions and labour -- Oviducts -- Myosalpinx contractions are essential for egg transport along the oviduct and are disrupted in reproductive tract diseases -- PART IV: Blood vessels -- Artery -- Cellular and Ionic Mechanisms of Arterial Vasomotion -- Vein -- Venous Vasomotion -- Microvasculature -- Role of pericytes in the initiation and propagation of spontaneous activity in the microvasculature -- Lymphatic vessels -- Lymphatic vessel pumping -- PART V: Airways -- Regulation of airway smooth muscle contraction in health and disease.
520	3		_aThis book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, phasic muscle, tonic muscle, renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike. .
650		7	_2embne _aMúsculos _xEnfermedades _9169472
650		7	_2embne _9146529 _aTics
700	1		_aHashitani, Hikaru _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLang, Richard J _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811358944
776	0	8	_iPrinted edition: _z9789811358968
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-5895-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b01/2020 _ek _zSI