000			03932nam a2200409 i 4500
988			_aSpringer_BiomedLife_2019
999			_c115797 _d115797 _x1
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003			ESmaUEC
005			20230110040238.0
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008			190909s2019 gw | s |||| 0|eng d
020			_a9783030211622
024	7		_a10.1007/978-3-030-21162-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP752.C37 _b2019 EB
245	0	0	_aBioactive Ceramides in Health and Disease : _bIntertwined Roles of Enigmatic Lipids _cedited by Johnny Stiban.
250			_a1st ed. 2019.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XII, 153 páginas) _b 31 ilustraciones, 14 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1159
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPreface -- About the Editor -- Introduction: Enigmas of Sphingolipids -- Prokaryotic and Mitochondrial Lipids: A Survey of Evolutionary Origins -- Ceramide Channels -- A Stroll Down the CerS Lane -- The Role of Ceramide 1-Phosphate in Inflammation, Cellular Proliferation, and Wound Healing -- Ceramide Domains in Health and Disease: a Biophysical Perspective -- Sphingolipids as Biomarkers of Disease -- Inflammatory Ocular Diseases and Sphingolipid Signaling -- Index.
520	3		_aThis book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations. .
650		7	_aLípidos _2embne _9142933
700	1		_aStiban, Johnny _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030211615
776	0	8	_iPrinted edition: _z9783030211639
776	0	8	_iPrinted edition: _z9783030211646
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-21162-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b12/2019 _eIG _zSI