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020 _a9783030195151
024 7 _a10.1007/978-3-030-19515-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC600
_b2019 EB
245 0 0 _aNeuroimmune Diseases :
_bFrom Cells to the Living Brain
_cedited by Hiroshi Mitoma, Mario Manto.
250 _a1st ed. 2019.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (VII, 827 páginas)
_b 96 ilustraciones, 77 ilustraciones a color
336 _aTexto
_btxt
_2rdacontent
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aContemporary Clinical Neuroscience
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _a1. Overview of mechanisms underlying neuroimmune diseases -- 2. Roles of interleukines in neurological autoimmunity -- 3. Roles of regulatory T cells in neurological autoimmunity -- 4.Immune tolerance triggering neurological autoimmunity -- 5. Disruption of blood-brain barrier and blood-nerve barrier: a key step in development of immune-mediated neurological diseases -- 6. Pathological mechanisms underlying production of autoantibodies -- 7. Significance of autoantibodies: cause or result? -- 8. Multiple actions of microglia -- 9. Autoimmune astropathy -- 10. Genetic factors indicating susceptibility to neurological diseases -- 11. General principles of immunotherapy -- 12. Multiple sclerosis -- 13. Neuromyelitis optica: Diagnosis and therapies -- 14. Atypical inflammatory demyelinating syndrome -- 15. Central nervous system vasculitis -- 16. Neuro-Beçhet and Sjőgren disease -- 17. Immune-mediated cortical encephalopathy (Limbic encephalitis) -- 18. Immune-mediated cerebellar ataxias -- 19. Stiff-Person syndrome -- 20. Guillain-Barré syndrome -- 21. Chronic inflammatory demyelinating polyneuropathy: Diagnosis and therapy -- 22. Immune-mediated disorders of neuro-muscular junctions -- 23. Myositis -- 24. Infection-related immune diseases -- 25. Paraneoplastic neurological syndromes; Diagnosis and Therapies.
520 3 _aA translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases.
650 7 _aEnfermedades autoinmunes
_0http://scigraph.springernature.com/things/product-market-codes/B18006
_2embne
_9143353
700 1 _aMitoma, Hiroshi
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aManto, Mario
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_984532
776 0 8 _iPrinted edition:
_z9783030195144
776 0 8 _iPrinted edition:
_z9783030195168
776 0 8 _iPrinted edition:
_z9783030195175
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-19515-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _dz
_b12/2019
_eIG
_zSI