000			04211nam a2200373 c 4500
988			_aSpringer_BiomedLife_2019
999			_c115552 _d115552 _x1
001			115552
003			ESmaUEC
005			20230110040236.0
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007			cr nn nnnaamaa
008			190617s2019 ne a o |||| 0|eng d
020			_a9789400766495
024	7		_a10.1007/978-94-007-6649-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRA1255 _b2019 EB
245	0	0	_aVenom Genomics and Proteomics _cedited by P. Gopalakrishnakone, Juan J. Calvete.
264		1	_aDordrecht _bSpringer Netherlands _c2019
300			_a1 recurso en línea (XX, 480 páginas) _b 30 ilustraciones, 15 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aToxinology _x2542-761X
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aDeadly Innovations: Unraveling the Molecular Evolution of Animal Venoms -- Squamate Reptile Genomics and Evolution -- Venoms of Colubrids -- Phylogenetics of Scorpions of Medical Importance -- Scorpion Venom Gland Transcriptomics and Proteomics: An Overview -- Brown Spider Venom: The Identification and Biotechnological Potential of Venom Toxins -- Venom Toxins of Fire Ants -- The Platypus: A Venomous Mammal -- Structure-Function Relationship of Modular Domains of P-III Class -- Snake Venom Metalloproteinases -- Biological Activities and Assays of the Snake Venom Metalloproteinases (SVMPs) -- Three-Dimensional Structures and Mechanisms of Snake Venom Serine Proteinases, Metalloproteinases, and Phospholipase A2s -- Structure-Function Relationship in Heterodimeric Neurotoxin PLA2s from Viperidae Snakes Inhabiting Europe, South America, and Asia -- Snake Venom Phospholipase A2: Evolution and Diversity. - Automated Mass Fingerprinting of Venoms in Nanogram Range: Review of Technology -- Snake Venom Peptidomics -- Snake Venom Proteopeptidomics: What Lies Behind the Curtain -- Shotgun Approaches for Venom Analysis -- Purinergic Mechanisms of Prey Acquisition by Venomous Organisms -- Applications of Snake Toxins in Biomedicine -- Industrial Production and Quality Control of Snake Antivenoms.
520	3		_aIn recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
650		7	_2embne _9138524 _aVenenos
700	1		_aGopalakrishnakone, P. _eeditor _4http://id.loc.gov/vocabulary/relators/edt _994194
700	1		_aCalvete, Juan J _eeditor _4http://id.loc.gov/vocabulary/relators/edt _947230
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-94-007-6649-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b12/2019 _ek _zSI