000			02886nam a2200397 c 4500
988			_aSpringer_BiomedLife_2019
999			_c115539 _d115539 _x1
001			115539
003			ESmaUEC
005			20230110040235.0
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
008			190606s2019 gw a o |||| 0|eng d
020			_a9783030170868
024	7		_a10.1007/978-3-030-17086-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP623 _b2019 EB
245	0	0	_aMolecular Biology of Long Non-coding RNAs _cedited by Ahmad M. Khalil.
250			_a2nd ed. 2019.
264		1	_aCham _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VII, 187 páginas) _b 10 ilustraciones, 9 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPreface -- Chromatin regulation by long non-coding RNAs -- Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs -- Roles of long non-coding RNAs in X-chromosome inactivation -- Roles of Long Non-Coding RNAs in Genomic Imprinting -- Dysregulation of long noncoding RNAs in human disease -- Functions of long non-coding RNAs in non-mammalian systems -- Emerging technologies to study long non-coding RNAs -- Long non coding RNAs and nuclear body formation and function -- The role of long non-coding RNAs in immunity -- Novel methods to study long non-coding RNAs -- OMICs of long non-coding RNAs -- Cancer epigenetics and long non-coding RNAs -- Roles of long non-coding RNAs in human development -- Index.
520	3		_aThis second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.
650		7	_2embne _aARN _9144940
700	1		_aKhalil, Ahmad M _eeditor _4http://id.loc.gov/vocabulary/relators/edt _984886
776	0	8	_iPrinted edition: _z9783030170851
776	0	8	_iPrinted edition: _z9783030170875
776	0	8	_iPrinted edition: _z9783030170882
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-17086-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b12/2019 _ek _zSI