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710	2		_aSpringerLink (Online service) _9106996
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020			_a9783030215408
024	7		_a10.1007/978-3-030-21540-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280.L5 _b2019 EB
245	0	0	_aHepatocellular Carcinoma : _bTranslational Precision Medicine Approaches _cedited by Yujin Hoshida.
250			_a1st ed. 2019.
264		1	_aCham _bSpringer International Publishing : _bImprint: Humana _c2019.
300			_a1 recurso en línea (XV, 364 páginas) _b 56 ilustraciones, 37 ilustraciones a color.
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMolecular and Translational Medicine _x2197-7852
490	0		_aMedicine (Springer-11650)
505	0		_aPart 1: Clinical demographics and management -- 1. Risk Factors of Hepatocellular Carcinoma for Precision Personalized Care -- 2. Hepatocellular Carcinoma Surveillance and Staging -- 3. Changing Epidemiology of Hepatocellular Carcinoma and Role of Surveillance -- Part 2: Diagnosis and prognostication -- 4. Radiological diagnosis and characterization of HCC -- 5. Analysis of Hepatocellular Carcinoma Tissue for Biomarker and Therapeutic Target Discovery -- 6. Molecular subtypes and genomic signatures of hepatocellular carcinoma for prognostication and therapeutic decision making -- 7. Liquid Biopsy in Hepatocellular Carcinoma -- Part 3: Treatment -- 8. Surgical Therapies in Hepatocellular Carcinoma -- 9. Interventional Radiologic Therapies for Hepatocellular Carcinoma: From Where We Began To Where We Are Going -- 10. Precision Locoregional Therapies for Hepatocellular Carcinoma: Percutaneous Ablation and Radiotherapy -- 11. Molecular-targeted therapies in hepatocellular carcinoma -- 12. Immune therapies -- 13. Prevention Strategies for Hepatocellular Carcinoma -- Part 4: Molecular pathogenesis and therapeutic discovery -- 14. Molecular Alterations and Heterogeneity in Hepatocellular Carcinoma -- 15. Stromal and Immune Drivers of Hepatocarcinogenesis -- 16. Experimental Models for Preclinical Research in Hepatocellular Carcinoma.
520	3		_aThis book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.
988			_aSpringer_Medicine_2019
650		7	_2embne _aHígado _xCáncer _9413204
700	1		_aHoshida, Yujin _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030215392
776	0	8	_iPrinted edition: _z9783030215415
776	0	8	_iPrinted edition: _z9783030215422
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-21540-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b11/2019 _ea _zSI