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020 _a9783030237653
024 7 _a10.1007/978-3-030-23765-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC271.I45
_b2020 EB
245 0 0 _aCurrent Immunotherapeutic Strategies in Cancer
_cedited by Matthias Theobald.
250 _a1st ed. 2020
264 1 _aCham
_bSpringer International Publishing
_c2020.
300 _a1 recurso en línea (V, 187 páginas)
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aRecent Results in Cancer Research
_x0080-0015
_v214
490 0 _aMedicine (Springer-11650)
505 0 _aCurrent Development of Monoclonal Antibodies in Cancer Therapy -- Clinical Experience with Bispecific T-Cell Engagers -- Advances and challenges of CAR-modified T cells in clinical trials -- Targeting Cancer with Genetically Engineered TCR-T Cells -- Tailored Vaccines Based on Patient's Cancer Mutanome -- Next-Generation Checkpoint Inhibitors and Immune Agonists.
520 3 _aThis book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient's cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment. Written by leading international experts and providing up-to-date information on emerging strategies, such as oncolytic virus-based therapy, epigenetic therapy, and combination therapy, the book appeals to all those with an interest in immunotherapy as it comes of age.
988 _aSpringer_Medicine_2020
650 7 _aCáncer
_xInmunoterapia
_2embne
_9348509
700 1 _aTheobald, Matthias
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030237646
776 0 8 _iPrinted edition:
_z9783030237660
776 0 8 _iPrinted edition:
_z9783030237677
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-23765-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
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998 _aSI
_cm
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