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| 988 | _aSpringer_Medicine_2019 | ||
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| 020 | _a9783319312156 | ||
| 024 | 7 |
_a10.1007/978-3-319-31215-6 _2doi |
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_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC |
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| 050 | 4 |
_aRC271.N46 _b2019 EB |
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| 245 | 0 | 0 |
_aTumor Angiogenesis : _bA Key Target for Cancer Therapy _cedited by Dieter Marmé |
| 264 | 1 |
_aCham _bSpringer International Publishing _c2019. |
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| 300 | _a1 recurso en línea | ||
| 336 |
_2rdacontent _aTexto _btxt |
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_2rdamedia _aelectrónico _bc |
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_2rdacarrier _arecurso electrónico _bcr |
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_atext file _bPDF |
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| 490 | 0 | _aMedicine (Springer-11650) | |
| 520 | 3 | _aUnderstanding of the molecular mechanisms of tumor development has increased considerably in recent years. As a consequence, the development of targeted therapies has proceeded rapidly, contributing to new drugs against cancer which are now under clinical investigation. Among these new therapies, anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer. This is due to the fact that tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented. | |
| 650 | 7 |
_2embne _aInhibidores de la neovascularización _9671432 |
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| 650 | 7 |
_2embne _9174085 _aCáncer _xTratamiento |
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| 650 | 7 |
_2embne _aOncología _9139207 |
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| 700 | 1 |
_aMarmé, Dieter _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 773 | 0 | _tSpringer Nature Living Reference | |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-31215-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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