000			03816nam a2200373 c4500
710	2		_aSpringerLink (Online service) _9106996
999			_c115109 _d115109 _x1
001			115109
003			ES-MaUEC
005			20230102113650.0
006			a||||fo|||| 00| 0
007			cr nn nnnanaaa
008			190821s2019 gw a o |||| 0|eng d
020			_a9783030226961
024	7		_a10.1007/978-3-030-22696-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP572.A54 _b2019 EB
245	0	0	_aAngiotensin-(1-7) : _bA Comprehensive Review _cedited by Robson Augusto Souza Santos.
250			_a1st ed. 2019.
264		1	_aCham _bSpringer International Publishing _c2019.
300			_a1 recurso en línea (XIII, 240 páginas) _b 33 ilustraciones, 23 ilustraciones a color.
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aINTRODUCTION -- 1.ANGIOTENSIN-(1-7) FORMATION AND METABOLISM -- Part I. TOOLS FOR STUDYING ANG-(1-7) -- 2. Pharmacological Tools-RAS -- 3. Genetic Models (ACE2 Models, MAS Models, Ang-(1-7) Models) -- Part II. ACTIONS OF ANGIOTENSIN-(1-7) -- 4. Brain (Ang-(1-7) Metabolism in the Brain, Ang-(1-7) Location in the Brain, MAS Location in the Brain, Ang-(1-7) Actions in the Brain, Cardiovascular Effects of Angiotensin-(1-7) at Specific Medullary Sites, Cardiovascular Effects of Angiotensin-(1-7) at Specific Hypothalamic Sites, Other Angiotensin-(1-7) Effects in the Brain, Neurotransmitter / Neuromodulator Effects of Ang-(1-7) -- 5. Heart (B1 Coronary vessels & Cardiomyocytes) -- 6. Ang-(1-7) and Cardioprotection -- 7. Blood Vessels -- 8. Kidney -- 9. Lung -- 10. Endocrine System -- 11. Skeletal Muscle System -- 12. Liver -- 13. Angiotensin-(1-7) and inflammation -- 14. J. Angiotensin-(-1-7) and Cancer -- 15. CONCLUDING REMARKS -- ACKNOWLEDGMENTS.
520	3		_aThis is the first book addressing in full the most important aspects of the angiotensin-(1-7), the key peptide of the protective axis and the main component in the new modulatory concept of the renin-angiotensin system. It features a detailed review of angiotensin-(1-7) and its receptor Mas, comprising the historical background, enzymatic pathways for generation, functions, integrative aspects of its protective profile, and its therapeutic potential. It also encompasses a comprehensive presentation of current knowledge about its widespread biological actions on several tissues, as well as the most recent scientific achievements, emerging from preclinical and clinical trials. Dr. Santos is a renowned researcher on the Renin-Angiontensin system, with remarkable achievements regarding the role of peptides such as alamandine and angiontensin-(1-7). He has also worked on the potential clinical applicability of angiotensin-(1-7)-related drugs for cardiovascular diseases. He has an extensive publication record in the field, including the publication of the book The Protective Arm of the Renin Angiotensin System (Academic Press, 2015). Angiotensin-(1-7) will make a unique contribution to the literature and will be an important resource for biomedical students and researchers, medical practitioners and any other professional interested in this peptide and its role in the renin-angiotensin system.
650		7	_aAngiotensina _9671626 _2embne
700	1		_aSantos, Robson Augusto Souza _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030226954
776	0	8	_iPrinted edition: _z9783030226978
776	0	8	_iPrinted edition: _z9783030226985
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-22696-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_Medicine_2019
998			_aSI _cm _dz _feng _ggw _h0 _b11/2019 _ea _zSI