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020			_a9783030144050
024	7		_a10.1007/978-3-030-14405-0 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aR853.C55 _b2019 EB
100	1		_aYajnik, Santosh _9670851
245	1	0	_aLandmark Trials in Oncology _cby Santosh Yajnik.
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2019.
300			_aIX, 325 páginas 120 ilustraciones, 70 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aIntroduction to Landmark Trials in Oncology -- Landmark Trials in Breast Cancer -- Landmark Trials in Lung Cancer -- Landmark Trials in Selected Genitourinary Malignancies -- Landmark Trials in Selected Gastrointestinal Cancers -- Landmark Trials in Selected Gynecologic Cancers -- Landmark Trials in Selected Head and Neck Cancers -- Landmark Trials in Selected Lymphomas -- Landmark Trials in Selected Central Nervous System Tumors -- Landmark Trials in Selected Adult Soft Tissue Sarcomas.
520	3		_aThis book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed more by the clinical trial than oncology. Each primary cancer site has a remarkable story that can be told through clinical trials. For example, patients who presented decades ago with soft tissue sarcoma of the extremities would invariably undergo limb amputation. The landmark National Cancer Institute study by Rosenberg et al. randomized patients to limb sparing surgery followed by adjuvant radiation therapy compared with limb amputation. This study helped change the standard of care by allowing most patients to retain their functioning limbs with an improvement in quality of life and no compromise in overall survival. Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed. Because oncology is multidisciplinary, this book should be of interest for radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the landmark trials that have shaped oncology.
988			_aSpringer_Medicine_2019
650		7	_2embne _aEnsayos clínicos _9144524
650		7	_2embne _aOncología _9139207
776	0	8	_iPrinted edition: _z9783030144043
776	0	8	_iPrinted edition: _z9783030144067
776	0	8	_iPrinted edition: _z9783030144074
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-14405-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _feng _ggw _h0 _b09/2019 _ek _zSI