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008			190315s2019 si a o |||| 0|eng d
020			_a9789811358777
024	7		_a10.1007/978-981-13-5877-7 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC270 _b2019 EB
245	0	0	_aMolecular Diagnostics in Cancer Patients _cedited by Kamla Kant Shukla, Praveen Sharma, Sanjeev Misra.
264		1	_aSingapore _bSpringer Singapore : _bImprint: Springer _c2019.
300			_aVIII, 341 páginas 45 ilustraciones, 43 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aIntroduction of molecular diagnostics -- Molecular Diagnostics in Bladder cancer -- Molecular Diagnostics in Lung cancer -- Molecular Diagnostics in Brain cancer -- Molecular Diagnostics in Melanoma -- Molecular Diagnostics in Breast cancer -- Molecular Diagnostics in Non-Hodgkin lymphoma -- Molecular Diagnostics in Cervical cancer -- Molecular Diagnostics in Colorectal cancer -- Molecular Diagnostics in Pancreatic cancer -- Molecular Diagnostics in Oral cancer -- Molecular Diagnostics in Prostate cancer -- Molecular Diagnostics in Kidney cancer -- Molecular Diagnostics in Skin cancer -- Molecular Diagnostics in Leukaemia -- Molecular Diagnostics in Thyroid cancer -- Molecular Diagnostics in Liver cancer -- Molecular Diagnostics in Uterine cancer -- Molecular Diagnostics in Ovarian cancer -- Pharmacogenomics Testing for Medication & Drug Response.
520	3		_aThis book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.
988			_aSpringer_Medicine_2019
650		7	_aCáncer _2embne _9182544 _xDiagnóstico
650		7	_aDiagnóstico molecular _2embne _9158916
700	1		_aShukla, Kamla Kant. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSharma, Praveen. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMisra, Sanjeev. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811358760
776	0	8	_iPrinted edition: _z9789811358784
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-5877-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _feng _ggw _h0 _b09/2019 _ek _zSI