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008			190513s2019 gw a o |||| 0|eng d
020			_a9783030114466
024	7		_a10.1007/978-3-030-11446-6 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC862.I53 _b2019 EB
245	0	0	_aBiomarkers in Inflammatory Bowel Diseases _cedited by Nik Sheng Ding, Peter De Cruz.
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2019.
300			_aXVII, 365 páginas 35 ilustraciones, 30 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aPart I: Introduction -- nflammatory bowel disease - more than meets the eye - Clinical risk factors - lessons from epidemiology -- Clinical trial design for biomarker discovery -- Database/ big data meets real world -- Patient reported outcomes -- Part II: Biomarkers - Prognostic vs Predictive -- Biomarkers for remote monitoring -- Disease modification -- Part IIV: Crohn's disease -- Luminal Crohn's disease-. Perianal CD -- Fibrosis/ strictures in CD -- Post-op Crohn's disease -- Part IV: Ulcerative colitis -- UC surveillance -- Acute severe UC -- Chronic active UC -- Pouchitis -- Refractory proctitis -- Feacal microbiota transplantation -- Primary sclerosing cholangitis -- Extraintestinal manifestations of IBD -- Part V: Specialised scenarios -- Pregnancy -- Nutrition -- TDM -- Biomarkers to quantify immune response -- Drug toxicity -- Part VI:Scientific -- Exposome and diet -- Microbiota -- Metabonomics -- Immunology -- Genomics -- Systems Biology in Biomarker research -- Part VII: Ideal tools for investigation in the future.
520	3		_aThis book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice. This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline. The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.
988			_aSpringer_Medicine_2019
650		7	_2embne _aEnfermedad inflamatoria intestinal _xAspectos moleculares _9160162
653		0	_aGastroenterology.
653		0	_aMicrobial genetics.
700	1		_aSheng Ding, Nik. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aDe Cruz, Peter. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _982518
776	0	8	_iPrinted edition: _z9783030114459
776	0	8	_iPrinted edition: _z9783030114473
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-11446-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _feng _ggw _h0 _b09/2019 _ek _zSI