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020			_a9783319981437
024	7		_a10.1007/978-3-319-98143-7 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRB150 .F52 _b2019 EB
245	0	0	_aFibrosis in Disease : _bAn Organ-Based Guide to Disease Pathophysiology and Therapeutic Considerations _cedited by Monte S. Willis, Cecelia C. Yates, Jonathan C. Schisler
264		1	_aCham _bSpringer International Publishing : _bImprint: Humana Press _c2019
300			_a1 recurso en línea (XIX, 471 páginas 62 ilustraciones, 59 ilustraciones a color)
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	1		_aMolecular and Translational Medicine, _x2197-7852
490	0		_aMedicine (Springer-11650)
505	0		_aIntroduction -- The Role of Chemokines in Fibrotic dermal remodeling and wound healing -- Fibrosis and immune dysregulation in systemic sclerosis -- Macrophage Plasticity in Skin Fibrosis -- Fibrotic Signaling in the Lung -- Pulmonary Matrikines: Origin, Function and Contribution to Fibrotic and Non-Fibrotic Lung Disease -- The Role of Mast Cells in the Pathophysiology of Pulmonary Fibrosis -- PERICYTES AND T CELLS IN LUNG INJURY AND FIBROPROLIFERATION -- Emerging Therapeutic Targets and Therapies in Idiopathic Pulmonary Fibrosis -- Dynamic reciprocity- the role of the extracellular matrix microenvironment in amplifying and sustaining pathological lung fibrosis -- Fibrotic Signaling in Cardiomyopathies -- WNT SIGNALING AND CARDIAC FIBROSIS -- Matrix metalloproteinase-9-dependent mechanisms of reduced contractility and increased stiffness in the aging heart -- Using peptidomics to identify extracellular matrix-derived peptides as novel therapeutics for cardiac disease -- Vascular Fibrosis and Disease -- Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment -- Tipping the balance from angiogenesis to fibrosis in chronic kidney disease -- Fibrotic Remodeling in Exudative (Wet) Macular Degeneration.
520	3		_aThis book serves as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. It provides new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It also highlights the many new areas of therapeutic investigation currently underway. Lastly, it touches upon newly emerging fields and investigates the role of fibrosis in macular degeneration and cancer metastasis. Chapters are written by established experts in their fields, including clinicians, cardiologists, cardiovascular surgeons, pathologists, general practitioners, and translational biomedical researchers in a wide range of disciplines. However, the material also applies to a broader audience, including medical residents, fellows, and M.D. or Ph.D. post-doctoral research fellows. While comprehensive, this book presents the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience.
988			_aSpringer_Medicine_2019
650		7	_aFibrosis _9148433 _2embne
700	1		_aWillis, Monte S. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aYates, Cecelia C. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSchisler, Jonathan C. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783319981420
776	0	8	_iPrinted edition: _z9783319981444
830		0	_aMolecular and Translational Medicine, _x2197-7852 _9133632
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-98143-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _feng _ggw _h0 _b07/2019 _eu _zSI