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020 _a9783030039349
024 7 _a10.1007/978-3-030-03934-9
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC600
_b2019 EB
245 0 0 _aGenetics of Rare Autoimmune Diseases
_cedited by Javier Martín, Francisco David Carmona
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _a1 recurso en línea (VIII, 240 páginas 12 ilustraciones, 10 ilustraciones a color)
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 1 _aRare Diseases of the Immune System,
_x2282-6505
490 0 _aMedicine (Springer-11650)
505 0 _aPreface -- I Connective tissue diseases -- 1 Systemic lupus erythematosus (Possible contributors: Maria Teruel & Marta Alarcón) -- 2 Systemic sclerosis (Possible contributors: Elena Lopez-Isac & Marialbert Acosta) -- 3 Behçet's disease (Possible contributors: Lourdes Ortiz & Francisca Gonzalez-Ecribano) -- 4 Sjogren's síndrome (Possible contributors: Pers JO, Renaudineau Y. & Xavier Marriet) -- 5 Polymiositis/Dermatomyositis (Possible contributors: Ana Márquez & Albert Selva) -- II Autoimmune Vasculitis -- 6 ANCA-associated Vasculitis (Possible contributors: Augusto Vaglio) -- 7 Giant Cell Arteritis (Possible contributors: F. David Carmona & Miguel Ángel Gónzalez-Gay) -- 8 Takayasu's Arteritis (Possible contributors: Amr H. Sawalha) -- 9 Kawasaki's Disease (Possible contributors: David Burgner) -- III Gastrointestinal and Liver/hepatic Autoimmune Conditions -- 10 Primary Biliary Cirrhosis, Sclerosing Cholangitis, and Autoimmune Hepatitis (Possible contributors: G.J. Webb & G.M. Hirschfield) -- IV Central and Peripheral Nervous System -- 11 Multiple Sclerosis (Possible contributors: Antonio Alcina & Fuencisla Matesanz) -- 12 Myastenia Gravis (Possible contributors: Güher Saruhan Direskeneli) -- V Shared Gentetic Component -- 13 Common Genetic Component in Autoimmunity (Possible contributors: Alexandra Sasha) -- Subject Index.
520 3 _aThe main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact. General sections include different chapters on single entities as systemic lupus and sclerosis, Behçet's disease, Sjogren's syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.
988 _aSpringer_Medicine_2019
650 7 _2embne
_aEnfermedades autoinmunes
_9143353
650 7 _2embne
_9160812
_aEnfermedades raras
700 1 _aMartín, Javier.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aCarmona, Francisco David.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030039332
776 0 8 _iPrinted edition:
_z9783030039356
830 0 _aRare Diseases of the Immune System,
_x2282-6505
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-03934-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
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998 _dz
_feng
_ggw
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_b07/2019
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