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020 _a9783030020507
024 7 _a10.1007/978-3-030-02050-7
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH588.S83
_b2019 EB
100 1 _aWartenberg, Hubert
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9687094
245 1 4 _aThe Origin of a New Progenitor Stem Cell Group in Human Development :
_bAn Immunohistochemical-, Light- and Electronmicroscopical Analysis
_cby Hubert Wartenberg, Andreas Miething, Kjeld Møllgård
264 1 _aCham
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (XII, 79 páginas)
_b78 ilustraciones, 2 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aAdvances in Anatomy, Embryology and Cell Biology
_x0301-5556
_v230
490 0 _aMedicine (Springer-11650)
505 0 _aChapter 1. Distribution of progenitor stem cells from the AMG-system an the adrenal -- Chapter 2. Development of the adrenal medulla and other endocrine glands -- Chapter 3. Final view on stem cell origin during human development.
520 3 _aThis book presents an overview of a new group of progenitor stem cells. Their origins were originally detected in light- and electron microscopical sections of plastic embedded human embryonal and fetal organs. The distribution of these cells can result in a large quantity of ectopic stem cells. The observation of these ectopic stem cells leads us to postulate the existence of a basic wave of stem cell progenitors. This process proceeds earlier and independently from germ cell migration. This first wave of progenitor stem cell migration initially reaches the peri-aortal AMG-region (Aortal-Mesonephric-Gonadal region). From here, some of these progenitor cells enter the aorta, are distributed through the vascular system and become the embryonal stem cells (reserve cells) in many peripheral tissues. A second part delivers progenitor cells for the adrenal 'anlage'. Within the peripheral Zona definitiva of the adrenal cortex the progenitor cells multiplicate and subsequently leave the adrenal cortex through a gate of the capsule. The progenitor cells arrive at the pre-aortal sympathic plexus ('second brain'). Within the plexus ganglia they form new organ-like clusters, the paraganglia. In a second process the progenitor cells (Chromaffine cells) enter sympathetic nerve bundles. Here an 'axonal migration' starts, which guides the progenitor cells to several peripheral organs. During this migration process the stem cells develop into their final state. In the adrenal cortex the ingrowing nerves guide the stem cells to the adrenal medulla. In the pancreas the ingrowing nerve fibers guide the stem cells to the islets. These newly detected stem cells represent a specific developmental step which is found only in humans. .
988 _aSpringer_Medicine_2019
650 7 _2embne
_aCélulas madre
_9160528
700 1 _aMiething, Andreas
_d1955-
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9687095
700 1 _aMøllgård, Kjeld
_d1942-
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9687096
710 2 _aSpringerLink (Online service)
_9106996
776 0 8 _iPrinted edition:
_z9783030020491
776 0 8 _iPrinted edition:
_z9783030020514
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-02050-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _dz
_b02/2023
_eb
_zSI